Diazoxide Impurity 2 CAS 54981-41-8
| CAS No. | 54981-41-8 |
| Molecular Formula | C8H8ClNO4S |
| Molecular Weight | 249.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Diazoxide Impurity 2 (CAS 54981-41-8) is a certified pharmaceutical impurity reference standard with the molecular formula C8H8ClNO4S and a molecular weight of 249.67 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Diazoxide Impurity 2 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 249.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO4S |
| Molecular Weight | 249.67 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Diazoxide Standards
- Diazoxide impurity 11 (CAS CATO-C4X-195211)
- Diazoxide impurity 5 (CAS 19185-77-4)
- Diazoxide impurity 10 (CAS CATO-C4X-195210)
- Diazoxide Impurity 20 (CAS CATO-C4X-195220)
- Diazoxide impurity 7 (CAS CATO-C4X-19527)
- Diazoxide D3 (CAS 1432063-51-8)
- Diazoxide-15N,13C2 (CAS 1329613-88-8)
- Diazoxide Impurity 1 (CAS 5800-59-9)
Recommended Standards
- Sulpiride impurity 15 (CAS 77718-16-2)
- Thiamethoxam Impurity 1 (CAS 131748-59-9)
- Diazepam Impurity 8 (CAS 784-38-3)
- Clothianidin (CAS 210880-92-5)
- Fedratinib Impurity 6 (CAS 936091-39-3)
- Cefotaxime impurity 94 (CAS 1950566-52-5)
- Apixaban Impurity 61 (CAS CATO-C4X-108861)
- 1-(6-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-methylpyridin-3-yl)ethan-1-amine (CAS 1355223-47-0)
- 4-Chloro-2-methylpyridine 1-oxide (CAS 696-08-2)
- 1-(3,4-Dichlorophenyl)-4,4-dimethyl-1,4-dihydropyrimidine-2-thiol (CAS 1142212-34-7)
- N-(4-Amino-2-methoxyphenyl)-2-phenoxyacetamide (CAS 861409-91-8)
- S-(-)-Warfarin-d5 (CAS 791013-22-4)
- 6,6-Dimethyl-3-(morpholine-4-carbonyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine (CAS 1384594-76-6)
- Des-Pro31-Tirzepatide (CAS CATO-CPTD788943)
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