4-Hydroxy-6-phenyl-2H-pyran-2-one CAS 5526-38-5
| CAS No. | 5526-38-5 |
| Molecular Formula | C11H8O3 |
| Molecular Weight | 188.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Hydroxy-6-phenyl-2H-pyran-2-one (CAS 5526-38-5) is a high-purity analytical reference standard with the molecular formula C11H8O3 and a molecular weight of 188.18 g/mol.
Structurally, 4-Hydroxy-6-phenyl-2H-pyran-2-one (C11H8O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 188.18 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Hydroxy-6-phenyl-2H-pyran-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8O3 |
| Molecular Weight | 188.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
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Recommended Standards
- 4-Hydroxy-5-phenylcyclopent-4-ene-1,3-dione (CAS 36394-22-6)
- 4-Hydroxyquinoline-7-carboxamide (CAS 220998-68-5)
- 4H-Imidazo[4,5,-i,j]-quinolin-2,6-(1H,5H)dione (CAS 75655-10-6)
- 4-Methoxyquinazoline-6-carbaldehyde (CAS 648449-03-0)
- 1-Methyl-4-nitro-1h-pyrrole-2-carboxamide (CAS 13138-77-7)
- N4,N4,N4',N4'-Tetrakis(4-iodophenyl)-[1,1'-biphenyl]-4,4'-diamine (CAS 1322605-30-0)
- 6-Chloro-4-cyclopropylpyridin-2-amine (CAS 1422039-90-4)
- (3,4-Dichlorophenyl)(2-(phenylamino)thiazol-5-yl)methanone (CAS 339008-00-3)
- 1-(4-Fluorobenzyl)-2-(thiophen-2-yl)-1H-benzo[d]imidazole (CAS 615281-45-3)
- Ciclesonide Impurity 2 (CAS 886861-17-2)
- 4-Bromo-3-(trifluoromethyl)phenol (CAS 320-49-0)
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- 4'-Propyl-[1,1'-bi(cyclohexan)]-4-one (CAS 87625-09-0)
- Mast Cell Degranulating Peptide HR-1 (CAS 80533-94-4)
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