5-Methyl-2-(3-(trifluoromethyl)phenyl)-1,2-dihydro-3H-pyrazol-3-one CAS 55347-03-0
| CAS No. | 55347-03-0 |
| Molecular Formula | C11H9F3N2O |
| Molecular Weight | 242.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Methyl-2-(3-(trifluoromethyl)phenyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 55347-03-0), molecular formula C11H9F3N2O and molecular weight 242.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Methyl-2-(3-(trifluoromethyl)phenyl)-1,2-dihydro-3H-pyrazol-3-one (C11H9F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Methyl-2-(3-(trifluoromethyl)phenyl)-1,2-dihydro-3H-pyrazol-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9F3N2O |
| Molecular Weight | 242.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 5-Methyl-1-(5-(trifluoromethyl)pyridin-2-yl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1171925-31-7)
- 3a-(Trifluoromethyl)-2,3,3a,4-tetrahydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-1-one (CAS 1191278-87-1)
- alpha-(Trifluoromethyl)-1-phenyl-1H-pyrazole-4-methanol (CAS 1275913-48-8)
- 1-(4-(Trifluoromethyl)benzyl)-1H-1,2,4-triazol-3-amine (CAS 1291723-68-6)
- 1-[1-methyl-5-(trifluoromethyl)-1h-1,3-benzodiazol-2-yl]ethan-1-one (CAS 1312139-07-3)
- 3-Oxo-1-(trifluoromethyl)-2,3,5,6,7,8-hexahydroisoquinoline-4-carbonitrile (CAS 1334490-86-6)
- 2-Benzyl-5-(trifluoromethyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 143706-79-0)
- 1-(4-(Trifluoromethyl)benzyl)-1H-1,2,3-triazol-4-amine (CAS 1510209-73-0)
Recommended Standards
- 4-Ethoxy-5-fluoro-1-(2-oxotetrahydrofuran-3-yl)pyrimidin-2(1H)-one (CAS 50992-27-3)
- methyl 3-fluoro-4-(2-methoxy-2-oxoethoxy)benzoate (CAS 2007909-62-6)
- 4-Cyclopropyl-6-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-3-amine (CAS 832739-88-5)
- Lisinopril Impurity 12 (CAS CATO-C4X-168112)
- 1-Acetylpiperidine (CAS 618-42-8)
- 5-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-methylthieno[2,3-c]isothiazol-4-amine (CAS 321430-77-7)
- Cyclopamine Tartrate (CAS 1178510-81-0)
- 4-Chloro-5,6-dimethyl-2-(trifluoromethyl)pyrimidine (CAS 175277-32-4)
- 6-Phenyl-2-(2-propoxybenzylidene)-2H-thiazolo[3,2-b][1,2,4]triazine-3,7-dione (CAS 609794-93-6)
- 2,5-Dichloro-N-(4-(2,4-dimethylphenyl)thiazol-2-yl)thiophene-3-carboxamide (CAS 476626-98-9)
- Ribavirin Impurity 13 (CAS CATO-C4X-141313)
- Higenamine Hydrochloride (CAS 11041-94-4)
- 4-(tert-Butyl)-1-cyclopropoxy-2-nitrobenzene (CAS 1243383-43-8)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
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