5-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-methylthieno[2,3-c]isothiazol-4-amine CAS 321430-77-7

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

5-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-methylthieno[2,3-c]isothiazol-4-amine (CAS 321430-77-7) is a high-purity analytical reference standard with the molecular formula C12H7ClF3N3S2 and a molecular weight of 349.78 g/mol.

The molecular framework of 5-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-methylthieno[2,3-c]isothiazol-4-amine (C12H7ClF3N3S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

CATO manufactures 5-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-methylthieno[2,3-c]isothiazol-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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