Lisinopril Impurity 12 CAS CATO-C4X-168112
| CAS No. | CATO-C4X-168112 |
| Molecular Formula | C8H13F3N2O3 |
| Molecular Weight | 242.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Lisinopril Impurity 12 (CAS CATO-C4X-168112) is a certified pharmaceutical impurity reference standard with the molecular formula C8H13F3N2O3 and a molecular weight of 242.20 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Lisinopril Impurity 12 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H13F3N2O3 |
| Molecular Weight | 242.20 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Lisinopril Standards
- Lisinopril Impurity 28 (CAS 1207346-27-7)
- Lisinopril EP Impurity A (CAS 5472-95-7)
- Lisinopril EP Impurity A (CAS 1012-05-1)
- Lisinopril EP Impurity H (CAS 138247-43-5)
- Lisinopril impurity 29 (CAS 1496563-44-0)
- Lisinopril Impurity 11 (CAS CATO-C4X-168111)
- Lisinopril (8R,S)-Diketopiperazine (Mixture of Diastereomers) (CAS 1092813-99-4)
- Lisinopril EP Impurity C (CAS 328385-86-0)
Recommended Standards
- methyl 3-fluoro-4-(2-methoxy-2-oxoethoxy)benzoate (CAS 2007909-62-6)
- H-Lys(Tfa)-OH (CAS 10009-20-8)
- 5-Methyl-2-(3-(trifluoromethyl)phenyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 55347-03-0)
- Tetradecylboronic acid (CAS 100888-40-2)
- HISTIDINE Impurity 13 (CAS CATO-C4X-323913)
- Rifampicin Impurity 4 (CAS 16783-99-6)
- Baricitinib Impurity 88 (CAS CATO-C4X-226088)
- 41446-63-3 3V3074NJ3L 7-Tetradecene, (7E)- 7-Tetradecene, (E)- UNII-3V3074NJ3L (CAS 41446-63-3)
- Isopropyl 4-(1H-pyrazol-4-yl)piperidine-1-carboxylate (CAS 1245645-53-7)
- 4-(((Tert-butoxycarbonyl)amino)methyl)bicyclo[2.2.1]Heptane-1-carboxylic acid (CAS 1956325-65-7)
- 4-Phenylthiazol-2-amine hydrobromide (CAS 34161-31-4)
- 2-(9,9'-Spirobi[fluoren]-2-yl)-4,6-diphenyl-1,3,5-triazine (CAS 1207176-84-8)
- N-(2-(2-Oxo-2-(((tetrahydrofuran-2-yl)methyl)amino)ethyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)-2-(m-tolyl)acetamide (CAS 1105250-62-1)
- Tirzepatide Impurity 52 (CAS CATO-C4X-324052)
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