Baclofen impurity 22 CAS 55591-37-2
| CAS No. | 55591-37-2 |
| Molecular Formula | C17H25ClN2 |
| Molecular Weight | 292.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Baclofen impurity 22 (CAS 55591-37-2) is a certified pharmaceutical impurity reference standard with the molecular formula C17H25ClN2 and a molecular weight of 292.85 g/mol.
Structurally, Baclofen impurity 22 (C17H25ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 292.85 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H25ClN2 |
| Molecular Weight | 292.85 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Baclofen Standards
- Baclofen Impurity 76 (CAS CATO-C4X-101276)
- Baclofen Impurity 59 (CAS CATO-C4X-101259)
- Baclofen impurity 9 (CAS 101104-10-3)
- Baclofen Impurity 66 (CAS CATO-C4X-101266)
- Baclofen Impurity 65 (CAS CATO-C4X-101265)
- Baclofen impurity 43 (CAS CATO-C4X-101243)
- Baclofen impurity 44 (CAS CATO-C4X-101244)
- Baclofen impurity 28 (CAS CATO-C4X-101228)
Recommended Standards
- rac 1-Lauroyl-3-chloropropanediol (CAS 20542-96-5)
- tert-Butyl[(6-chloronaphthalen-2-yl)oxy]dimethylsilane (CAS 1881290-40-9)
- Diiodoacetonitrile (CAS 959961-04-7)
- 2-[(6-chloropyrazolo[3,4-d]pyrimidin-1-yl)methoxy]ethyl-trimethyl-silane (CAS 2230521-64-7)
- Thiamine Nitrate EP Impurity A (CAS 2380-61-2)
- Maribavir Impurity 14 (CAS 142356-76-1)
- Barloxavir impurity 99 (CAS CATO-C4X-210899)
- 3-Methyl-5-nitrobenzaldehyde (CAS 107757-06-2)
- 2,2,2-Trifluoro-1-(1H-imidazol-2-yl)ethanol (CAS 105480-22-6)
- Benzyl 2-amino-3-hydroxypropanoate hydrochloride (CAS 879278-55-4)
- 6-Chloro-4-(o-tolyl)nicotinonitrile (CAS 825638-00-4)
- 5-Bromo-1,4-dihydro-1,4-epoxynaphthalene (CAS 136131-50-5)
- N-(m-tolyl)propionamide (CAS 705-47-5)
- Lixisenatide (CAS 320367-13-3（free base）)
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