3,5-Diiodo-D-thyronine CAS 5563-89-3
| CAS No. | 5563-89-3 |
| Molecular Formula | C15H13I2NO4 |
| Molecular Weight | 525.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3,5-Diiodo-D-thyronine (C15H13I2NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 3,5-Diiodo-D-thyronine (CAS 5563-89-3), a certified reference material (molecular formula C15H13I2NO4, MW 525.08 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,5-Diiodo-D-thyronine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H13I2NO4 |
| Molecular Weight | 525.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Diiodo Standards
- 3,5-Diiodo-DL-thyronine (CAS 534-51-0)
- 2,3-Diiodo-5-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1246088-65-2)
- 2,4-Diiodo-6-(methylsulfonyl)phenyl hexanoate (CAS 400087-36-7)
- 6,8-Diiodo-3-(2-oxo-2-(thiophen-2-yl)ethyl)quinazolin-4(3H)-one (CAS 669762-29-2)
- 5,7-Diiodo-3-(4-methoxybenzoyl)benzo[d]oxazol-2(3H)-one (CAS 861212-99-9)
- (R)-6,6'-Diiodo-4,4'-dimethyl-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol (CAS 2098225-21-7)
- (S)-6,6'-diiodo-4,4'-dimethyl-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol (CAS 2050190-03-7)
- Boc-3,5-diiodo-L-tyrosine (CAS 62129-53-7)
Recommended Standards
- 2-(Benzylsulfanyl)-5-(4-chlorophenyl)-4-{2'-fluoro-4'-propyl-[1,1'-biphenyl]-4-yl}pyrimidine (CAS 478248-93-0)
- 2-Chloro-3,4-bis((4-methoxybenzyl)oxy)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide (CAS 1225208-44-5)
- Levothyroxine Impurity 16 (CAS 4192-14-7)
- Pazopanib Impurity 39 (CAS 1252927-44-8)
- (4-Propyl-4h-1,2,4-triazol-3-yl)methanol (CAS 497855-00-2)
- KU-55933 (CAS 587871-26-9)
- tert-Butyl (3-methoxy-2-nitrophenyl)carbamate (CAS 158461-29-1)
- 1158-10-7 3,5-Ditpa 3,5-diiodo-4-(4-hydroxyphenoxy)hydrocinnamic acid 3,5-diiodothyropropanoic acid 3,5-diiodothyropropionic acid 3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid 3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propionic acid CHEBI:134267 DITPA (CAS 1158-10-7)
- 3,4-Dichloro-2-fluorotoluene (CAS 924626-74-4)
- 2,5-Dimethyl-3-methoxybenzophenone (CAS 750633-71-7)
- tert-Butyl 3-((4-(3-(((methylsulfonyl)oxy)methyl)azetidin-1-yl)phenyl)sulfonyl)azetidine-1-carboxylate (CAS 2173582-20-0)
- 1-Chloro-3-iodo-2-(trifluoromethyl)benzene (CAS 1007455-52-8)
- 3-Methylenepentane-1,5-diol (CAS 40760-35-8)
- Tirzepatide Impurity 51 (CAS CATO-C4X-324051)
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