Folic Acid Impurity 1 CAS 55645-40-4
| CAS No. | 55645-40-4 |
| Molecular Formula | C18H20N2O4 |
| Molecular Weight | 328.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Folic Acid Impurity 1.
Folic Acid Impurity 1 (CAS 55645-40-4) is a high-purity analytical reference standard with the molecular formula C18H20N2O4 and a molecular weight of 328.36 g/mol.
The molecular framework of Folic Acid Impurity 1 (C18H20N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20N2O4 |
| Molecular Weight | 328.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 2 |
Related Folic Standards
- Folic Acid Impurity 32 (CAS 4349-41-1)
- Folic Acid Impurity 36 (CAS CATO-C4X-139536)
- Folic Acid Impurity 47 (CAS CATO-C4X-139547)
- Folic Acid EP Impurity D (CAS 119-24-4)
- Folic Acid Impurity 14 (CAS 4230-33-5)
- Folic Acid Impurity 53 (CAS CATO-C4X-139553)
- DL-Folic Acid (CAS 65165-92-6)
- D-Folic Acid (CAS 65165-91-5)
Recommended Standards
- Ethyl 5,11-Dihydroindolo[3,2-b]carbazole-6-carboxylate (CAS 229020-86-4)
- H-Ala-Ala-Pro-Ala-OH (H-1425.0050) (CAS 53620-20-5)
- Ethyl 3-(2-ethoxy-2-oxoethyl)-1H-pyrrolo[3,4-b]quinoline-2(3H)-carboxylate (CAS 21902-16-9)
- HMBA (CAS 564468-51-5)
- 6-Hydroxy-2-[(2,3,4-trimethoxyphenyl)methylidene]-2,3-dihydro-1-benzofuran-3-one (CAS 256531-53-0)
- {4-[4-(Trifluoromethoxy)phenyl]phenyl}boronic acid (CAS 501944-50-9)
- 4-Ethyl-5-[2-(methylsulfanyl)phenyl]-4H-1,2,4-triazole-3-thiol (CAS 338967-83-2)
- 4-[(4-acetamidophenyl)amino]benzoic acid (CAS 852927-26-5)
- N-benzyl-N'-methyl-1-phenylmethanediamine (CAS CATO-C3D-262743)
- Decarboxamide Meprobamate (CAS 1471-56-3)
- Methyl (3-cyanophenyl)glycinate (CAS 126690-11-7)
- N-Cyclopropyl-4-methylpyrimidin-2-amine (CAS 1342994-39-1)
- 3-Methylbenzo[b]thiophene-2-carbonitrile (CAS 3216-49-7)
- Semaglutide impurity 57 (CAS 2773558-06-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com