Folic Acid Impurity 32 CAS 4349-41-1
| CAS No. | 4349-41-1 |
| Molecular Formula | C15H18N6O3 |
| Molecular Weight | 330.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Folic Acid Impurity 32 (CAS 4349-41-1), a pharmacopoeial impurity reference standard (molecular formula C15H18N6O3, MW 330.34 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Folic Acid Impurity 32 (C15H18N6O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H18N6O3 |
| Molecular Weight | 330.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 6 |
Related Folic Standards
- Folic Acid Impurity 36 (CAS CATO-C4X-139536)
- Folic Acid Impurity 1 (CAS 55645-40-4)
- Folic Acid Impurity 47 (CAS CATO-C4X-139547)
- Folic Acid EP Impurity D (CAS 119-24-4)
- Folic Acid Impurity 14 (CAS 4230-33-5)
- Folic Acid Impurity 53 (CAS CATO-C4X-139553)
- DL-Folic Acid (CAS 65165-92-6)
- D-Folic Acid (CAS 65165-91-5)
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Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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