Folic Acid EP Impurity D CAS 119-24-4
| CAS No. | 119-24-4 |
| Molecular Formula | C14H12N6O3 |
| Molecular Weight | 312.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Folic Acid EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Folic Acid EP Impurity D (CAS 119-24-4, C14H12N6O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Folic Acid EP Impurity D (C14H12N6O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 312.28 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C14H12N6O3 |
| Molecular Weight | 312.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 6 |
Related Folic Standards
- Folic Acid Impurity 47 (CAS CATO-C4X-139547)
- Folic Acid Impurity 1 (CAS 55645-40-4)
- Folic Acid Impurity 32 (CAS 4349-41-1)
- Folic Acid Impurity 36 (CAS CATO-C4X-139536)
- Folic Acid Impurity 14 (CAS 4230-33-5)
- Folic Acid EP Impurity F (CAS 1391194-56-1)
- Folic Acid Impurity 45 (CAS 1182291-60-6)
- Folic Acid Impurity 61 (CAS 99778-32-2)
Recommended Standards
- Decitabine Impurity 7 (CAS CATO-C4X-11377)
- Bosentan Impurity 8 (CAS 150728-12-4)
- Decitabine Impurity 4 (CAS CATO-C4X-11374)
- Uridine Impurity 20 (CAS CATO-C4X-233420)
- Tafluprost Impurity 28 (CAS CATO-C4X-216328)
- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
- Bendamustine Nitro Ethyl Ester Impurity (CAS 3543-72-4)
- Peramivir Impurity 62 (CAS 229614-93-1)
- 5-Carbamoyl-2-methylbenzoic acid (CAS 99357-88-7)
- 3-Cyano-2,6-difluorobenzoic acid (CAS 1314971-48-6)
- 2-[3-(4-Morpholinyl)propoxy]benzaldehyde hydrochloride (CAS 1609395-26-7)
- Edaravone Impurity 28 (CAS 53855-47-3)
- 1-Isopropylcinnolin-4(1H)-one (CAS 4964-40-3)
- ([D2]Gly4)-Cholecystokinin Octapeptide (sulfated) ammonium salt (CAS 1926163-74-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com