Ketotifen Impurity 18 CAS 5570-77-4
| CAS No. | 5570-77-4 |
| Molecular Formula | C6H12ClN |
| Molecular Weight | 133.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 133.62 g/mol gives Ketotifen Impurity 18 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ketotifen Impurity 18 (CAS 5570-77-4) is a certified pharmaceutical impurity reference standard with the molecular formula C6H12ClN and a molecular weight of 133.62 g/mol.
Owing to chlorine substitution, Ketotifen Impurity 18 is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 133.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ketotifen Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H12ClN |
| Molecular Weight | 133.62 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ketotifen Standards
- Ketotifen Impurity 22 (CAS 4506-53-0)
- Ketotifen Impurity 8 (CAS 59743-84-9)
- Ketotifen Hydrogen Fumarate (CAS 34580-14-8)
- Ketotifen Impurity 10 HCl (CAS CATO-C4X-204610)
- Ketotifen Impurity 11 Hemifumarate (CAS CATO-C4X-204611)
- Ketotifen EP Impurity F Hemifumarate (Mixture of Enol and Ketone) (CAS CATO-C4X-20466)
- Ketotifen Impurity 9 HCl (CAS 1227458-03-8)
- Ketotifen Impurity 24 (CAS CATO-C4X-204624)
Recommended Standards
- 57742-41-3 Benzyl chloride-|A-13C |A-Chlorotoluene-|A-13C (CAS 57742-41-3)
- 4-Chlorotoluene-d7 (CAS 84344-06-9)
- 1-(2-Chloroethyl)pyrrolidine (CAS 5050-41-9)
- Benzyl-d7 Chloride (CAS 59502-05-5)
- Dexrazoxane Impurity 30 (CAS 144236-91-9)
- Indobufen Impurity 6 (CAS 3087670-52-5)
- Rebamipide Impurity 34 (CAS CATO-C4X-152334)
- 2-Chloro-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethanol (CAS 1710202-24-6)
- (E)-2,6-Dichloro-4-(2-(dimethylamino)vinyl)nicotinonitrile (CAS 1175559-53-1)
- 4-(Difluoromethyl)-3-methoxy-6-(trifluoromethoxy)-2-(trifluoromethyl)pyridine (CAS 1804482-37-8)
- Benzyl 3-(chlorosulfonyl)piperidine-1-carboxylate (CAS 1311317-42-6)
- (2S,4S)-1-(tert-Butoxycarbonyl)-4-(2,4-dichloro-3,5-dimethylphenoxy)-2-pyrrolidinecarboxylic acid (CAS 1217856-90-0)
- N-(3-Cyanothiophen-2-yl)cyclopropanecarboxamide (CAS 865546-00-5)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
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