Ketotifen Impurity 11 Hemifumarate CAS CATO-C4X-204611
| CAS No. | CATO-C4X-204611 |
| Molecular Formula | 2*C19H19NOS |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Ketotifen Impurity 11 Hemifumarate (CAS CATO-C4X-204611), a pharmacopoeial impurity reference standard (molecular formula C19H19NOSC4H4O4, MW 425.50 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Ketotifen Impurity 11 Hemifumarate (C19H19NOSC4H4O4) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Ketotifen Impurity 11 Hemifumarate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | 2*C19H19NOS C4H4O4 |
| Molecular Weight | 425.50 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ketotifen Standards
- Ketotifen Impurity 23 (CAS 111428-56-9)
- Ketotifen Impurity 9 HCl (CAS 1227458-03-8)
- Ketotifen EP Impurity C (CAS 126939-27-3)
- Ketotifen EP Impurity E (CAS 1346603-71-1)
- Ketotifen EP Impurity F (Mixture of Enol and Ketone) (CAS 34580-09-1)
- Ketotifen (CAS 34580-13-7)
- Ketotifen Hydrogen Fumarate (CAS 34580-14-8)
- Ketotifen Impurity 19 (CAS 34580-20-6)
Recommended Standards
- Butylphthalide Impurity N4 (CAS 168288-19-5)
- Sarpogrelate Impurity 3 (CAS 135963-42-7)
- Lenvatinib Impurity 180 (CAS CATO-C4X-1140180)
- (1S,4S)-2-(4-Chlorobenzyl)-2,5-diaza-bicyclo[2.2.1]heptane (CAS 845866-65-1)
- 2-Chloro-D-phenylalanine (CAS 80126-50-7)
- 2-fluoro-4-(oxetan-3-yl)benzyl acetate (CAS CATO-C3D-262185)
- 3-(3-Chlorophenyl)-4-fluorobenzoic acid (CAS 1262005-93-5)
- N-tert-Butyl-N'-ethyl ethylenediamine (CAS 886500-74-9)
- 4-Chloro-7-methoxy-2-oxo-2H-chromene-3-carbaldehyde (CAS 122978-33-0)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com