2-(Piperazin-1-yl)pyrimidin-4-amine CAS 55745-87-4
| CAS No. | 55745-87-4 |
| Molecular Formula | C8H13N5 |
| Molecular Weight | 179.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(Piperazin-1-yl)pyrimidin-4-amine (CAS 55745-87-4), a certified reference material (molecular formula C8H13N5, MW 179.22 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, 2-(Piperazin-1-yl)pyrimidin-4-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 179.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H13N5 |
| Molecular Weight | 179.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 5 |
Related Piperazin Standards
- Piperazin-1-yl(1H-pyrrol-2-yl)methanone (CAS 1038285-42-5)
- 6-(Piperazin-1-yl)pyridin-2(1H)-one (CAS 108122-24-3)
- 6-(Piperazin-1-yl)pyrimidin-4-amine (CAS 1159820-98-0)
- 3-(Piperazin-1-yl)pyrazin-2-amine (CAS 59215-43-9)
- 4-(Piperazin-1-yl)pyrimidin-2-amine (CAS 59215-38-2)
- 6-(Piperazin-1-yl)pyridin-3-ol (CAS 287114-37-8)
- 1-(Piperazin-1-yl)cyclopentane-1-carbonitrile (CAS 885527-98-0)
- 5-(Piperazin-1-yl)furan-2-carbaldehyde (CAS 1094311-40-6)
Recommended Standards
- 2-(o-Tolylamino)propanoic acid (CAS 94800-25-6)
- 2-(Piperidin-1-yl)pyrimidin-4-ol (CAS 19810-81-2)
- 2-(M-tolylamino)acetohydrazide (CAS 2371-35-9)
- 2-(Piperidin-1-yl)pyrimidin-5-ol (CAS 809236-47-3)
- 5-Chloro-2-(pentyloxy)benzaldehyde (CAS 81995-30-4)
- 6-Chloro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (CAS 439215-13-1)
- 5-(Ethylamino)naphthalene-1-sulfonyl chloride (CAS 728864-90-2)
- 4-nitrophenyl dichloro(sulfanylidene)phosphinite (CAS 4225-51-8)
- Vonoprazan Impurity 209 (CAS 31543-47-2)
- 4-Fluoro-1-nitro-2-propoxybenzene (CAS 28987-45-3)
- 3-(Trifluoromethyl)azetidin-3-ol hydrochloride (CAS 848192-96-1)
- 2,4-Dichloro-6-(chloromethyl)-5-methylpyrimidine (CAS 430440-91-8)
- Octyloxy-acetaldehyde (CAS 53488-14-5)
- Fragment-[3-31]-Liraglutide (CAS CATO-C4X-199232)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com