Permethrin EP Impurity H CAS 56860-12-9
| CAS No. | 56860-12-9 |
| Molecular Formula | C16H18Cl4O3 |
| Molecular Weight | 400.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Permethrin EP Impurity H (CAS 56860-12-9), a pharmacopoeial impurity reference standard (molecular formula C16H18Cl4O3, MW 400.12 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Permethrin EP Impurity H (C16H18Cl4O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 400.12 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18Cl4O3 |
| Molecular Weight | 400.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
Related Permethrin Standards
- trans-Permethrin D6 (dimethyl D6) (CAS 82523-59-9)
- Permethrin-d5 (cis/trans mixture) (CAS 1794760-19-2)
- trans-Permethrin Solution, 10 mg/L, 2 x 5 ml (CAS 51877-74-8)
- Trans-Permethrin (CAS 61949-77-7)
- Cis-Permethrin (CAS 61949-76-6)
- Permethrin (CAS 52645-53-1)
- cis-Permethrin Solution, 10 mg/L, 2 x 5 ml (CAS 54774-45-7)
- Permethrin Impurity 11 (CAS 60066-84-4)
Recommended Standards
- 8-Bromo-4-((2,4-dichlorobenzyl)thio)cinnoline (CAS 92429-71-5)
- N,N-Dimethyl-L-tyrosine (CAS 17350-74-2)
- Perfluorohexanesulfonic Acid (CAS 355-46-4)
- 1-(4-Bromophenyl)-3-((4-bromophenyl)thio)propan-1-one (CAS 882749-13-5)
- Aprepitant Impurity 26 (CAS CATO-C4X-114126)
- Levofloxacin EP Impurity F (CAS 100986-89-8)
- Metaraminol Impurity 59 (CAS CATO-C4X-225259)
- 6-Aminopyridine-2,4(1H,3H)-dione (CAS 901768-65-8)
- Methyl (R)-3-amino-3-(2,4-dichlorophenyl)propanoate (CAS 1212989-20-2)
- Indapamide Impurity 17 (CAS 2494-79-3)
- Hydrazine Carbonate(70% in Water, ca. 7.3mol/L) (CAS 112077-84-6)
- (2-Hydroxy-3-methoxypropyl)(methyl)amine (CAS 60755-68-2)
- HR-73 (CAS 959571-93-8)
- Semaglutide impurity 91 (CAS CATO-C4X-222691)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com