Ceftizoxime Impurity 10 CAS 57028-71-4
| CAS No. | 57028-71-4 |
| Molecular Formula | C20H18N2O3S |
| Molecular Weight | 366.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ceftizoxime Impurity 10 (CAS 57028-71-4, C20H18N2O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Ceftizoxime Impurity 10 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 366.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ceftizoxime Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H18N2O3S |
| Molecular Weight | 366.43 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Ceftizoxime Standards
- Ceftizoxime Impurity 21 (CAS 36923-21-4)
- Ceftizoxime Ring-opening decarboxylation S-oxide 2 (CAS CATO-C4X-179340)
- Ceftizoxime Impurity 41 (CAS CATO-C4X-179341)
- Ceftizoxime Ring-opening decarboxylation S-oxide 1 (CAS CATO-C4X-179345)
- Ceftizoxime Impurity 70 (CAS CATO-C4X-179370)
- Ceftizoxime Impurity 90 (CAS CATO-C4X-179390)
- Ceftizoxime Impurity 93 (CAS CATO-C4X-179393)
- Ceftizoxime impurity 94 (CAS CATO-C4X-179394)
Recommended Standards
- Promethazine Impurity 46 (CAS CATO-C4X-141846)
- Benzylpenicillin Impurity 82 (CAS CATO-C4X-189982)
- Triphenyl(1-phenylethyl)phosphonium bromide (CAS 30537-09-8)
- Dehydrocorydaline (CAS 30045-16-0)
- Ozenoxacin Impurity 80 (CAS CATO-C4X-279680)
- Lifitegrast Impurity 80 (CAS CATO-C4X-240980)
- Sulindac EP Impurity B (CAS 59973-80-7)
- 2-((5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-1-phenylethan-1-one (CAS 332921-97-8)
- 2-Chloro-5,6,7,8,9,10-hexahydrocyclohepta[b]indole (CAS 17901-82-5)
- 4H-Thiazolo[5,4-b][1,4]thiazin-5(6H)-one (CAS 1522380-32-0)
- 5-Hydroxy-4,6-dimethylpyrimidin-2(1H)-one (CAS 87814-02-6)
- N-[(1R*,4R*)-4-Aminocyclohexyl]propionamide hydrochloride (CAS 1286273-38-8)
- 3-Chloro-2-fluoro-6-(trifluoromethyl)benzoyl chloride (CAS 261763-04-6)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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