1-Chloro-3-ethanesulfonylbenzene CAS 494870-50-7
| CAS No. | 494870-50-7 |
| Molecular Formula | C8H9ClO2S |
| Molecular Weight | 204.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Chloro-3-ethanesulfonylbenzene (C8H9ClO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-Chloro-3-ethanesulfonylbenzene (CAS 494870-50-7) is a high-purity analytical reference standard with the molecular formula C8H9ClO2S and a molecular weight of 204.67 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Chloro-3-ethanesulfonylbenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9ClO2S |
| Molecular Weight | 204.67 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-methyl-1-(methylsulfonyl)benzene (CAS 10200-36-9)
- 2-chloro-4,5-dimethoxybenzene-1-thiol (CAS 1094359-76-8)
- Methyl 4-chloro-5-ethylthiophene-2-carboxylate (CAS 1399655-29-8)
- 4-Chloro-5-propylthiophene-2-carboxylic acid (CAS 1399660-65-1)
- 2-Chloro-1-methyl-4-(methylsulfonyl)benzene (CAS 1671-18-7)
- 1-Chloro-2-(ethylsulfonyl)benzene (CAS 57321-29-6)
- 1-Chloro-4-(ethylsulfonyl)benzene (CAS 7205-80-3)
- Ethyl 5-chloro-4-methylthiophene-2-carboxylate (CAS 74598-04-2)
Recommended Standards
- 1-((Chloromethyl)sulfonyl)-4-methylbenzene (CAS 7569-26-8)
- 1-Chloromethyl-3-methanesulfonylbenzene (CAS 586373-70-8)
- (2-Chloroethylsulfonyl)benzene (CAS 938-09-0)
- 1-Phenylethane-1-sulfonyl chloride (CAS 58032-85-2)
- 2,2,2-Trifluoro-n-(2-methylpyridin-3-yl)acetamide (CAS 1260214-26-3)
- 6-(Methylamino)-2-phenylpyrimidine-4-carboxamide (CAS 1281872-50-1)
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- ethyl 7-bromopyrazolo[1,5-a]pyridine-2-carboxylate (CAS 1363382-88-0)
- 2-[3-(1,3-dimethyl-1h-pyrazol-4-yl)-1h-pyrazol-1-yl]acetic acid (CAS 1006464-37-4)
- 5-Methyl-2-(thiophen-2-yl)-3-(thiophen-3-yl)furan (CAS 89814-61-9)
- 4-[(tert-Butyldimethylsilyl)oxy]-2-chlorophenylboronic Acid (CAS 412343-21-6)
- 2-(Aminomethyl)-6-(difluoromethyl)-3-(trifluoromethyl)pyridine-5-acetic acid (CAS 1361821-61-5)
- 2-Methyl-4-[3-(trifluoromethyl)phenyl]thiomorpholine-3,5-dione (CAS 344266-26-8)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
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