Melphalan EP Impurity I CAS 573704-40-2
| CAS No. | 573704-40-2 |
| Molecular Formula | C14H21ClN2O3 |
| Molecular Weight | 300.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Melphalan EP Impurity I (CAS 573704-40-2), a pharmacopoeial impurity reference standard (molecular formula C14H21ClN2O3, MW 300.78 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C14H21ClN2O3, Melphalan EP Impurity I contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 300.78 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H21ClN2O3 |
| Molecular Weight | 300.78 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Melphalan Standards
- Melphalan Impurity 14 (CAS 1088-80-8)
- Melphalan DL-isomer (CAS 531-76-0)
- Melphalan (CAS 148-82-3)
- D-Melphalan (CAS 13045-94-8)
- Melphalan EP Impurity D (CAS 61733-01-5)
- Melphalan EP Impurity E (CAS CATO-C4X-198822)
- Melphalan EP Impurity H (CAS 88457-23-2)
- rac-Melphalan N-Oxide Impurity HCl (CAS 685898-44-6)
Recommended Standards
- MCPA-Butoxyethyl Ester (CAS 19480-43-4)
- N-Benzyl-5-chloro-3-isopropylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 1092443-98-5)
- Dapoxetine Impurity 32 (CAS CATO-C4X-143932)
- 2-((5-Amino-1,3,4-thiadiazol-2-yl)thio)-N-(4-chlorophenyl)acetamide (CAS 332114-17-7)
- Cefadroxil EP Impurity A(Amoxicillin EP Impurity I) (CAS 22818-40-2)
- Polaprezinc Impurity 1 (CAS 5323-50-2)
- Avibactam Impurity 72 (CAS CATO-C4X-134872)
- 1-((2-Carbamothioylhydrazono)methyl)isoquinoline-5-carboxylic acid (CAS 31181-06-3)
- Tert-butyl (2R,4S)-4-bromo-2-(methoxymethyl)pyrrolidine-1-carboxylate (CAS 2556993-39-4)
- Polaprezinc impurity 24 (CAS CATO-C4X-182124)
- 5-(4-Amino-1h-pyrazol-1-yl)-2,2-dimethylpentanenitrile (CAS 1487282-76-7)
- rel-Methyl (3R,7aR)-3-(hydroxymethyl)tetrahydro-1H-pyrrolizine-7a(5H)-carboxylate (CAS 2883770-97-4)
- 2-(Cyclohexylmethyl)-6-hydroxybenzaldehyde (CAS 1243347-85-4)
- Des-Lys20(Side Chain)-Semaglutide (CAS CATO-C4X-2226280)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com