Tolvaptan Impurity 39 CAS 1711-06-4
| CAS No. | 1711-06-4 |
| Molecular Formula | C8H7ClO |
| Molecular Weight | 154.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Tolvaptan Impurity 39 (CAS 1711-06-4, C8H7ClO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Tolvaptan Impurity 39 (C8H7ClO) contains a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Tolvaptan Impurity 39 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO |
| Molecular Weight | 154.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Tolvaptan Standards
- Tolvaptan Impurity 19 (CAS 933-88-0)
- Tolvaptan Impurity 18 (CAS 2486-75-1)
- Tolvaptan Impurity 21 (CAS 118-90-1)
- Tolvaptan Impurity 73 (CAS 1316312-24-9)
- Tolvaptan Impurity 17 (CAS 1975-51-5)
- Tolvaptan Impurity 49 (CAS 116815-03-3)
- Tolvaptan Impurity N1 (CAS 247237-56-5)
- Tolvaptan Impurity 16 (CAS 160129-45-3)
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