Quetiapine Fumarate EP Impurity B CAS 5747-48-8
| CAS No. | 5747-48-8 |
| Molecular Formula | C17H17N3S |
| Molecular Weight | 295.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Quetiapine Fumarate EP Impurity B (CAS 5747-48-8, C17H17N3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Quetiapine Fumarate EP Impurity B (C17H17N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Quetiapine Fumarate EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H17N3S |
| Molecular Weight | 295.40 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Quetiapine Standards
- Quetiapine impurity 82 (CAS CATO-C4X-124482)
- Quetiapine EP Impurity T (CAS 5747-46-6)
- Quetiapine impurity 75 (CAS CATO-C4X-124475)
- Quetiapine EP Impurity B-d8 (CAS 1189866-35-0)
- Quetiapine impurity 76 (CAS CATO-C4X-124476)
- Quetiapine DBTP N-Methyl Impurity (CAS 1977-09-9)
- Quetiapine Impurity 88 (CAS CATO-C4X-124488)
- Quetiapine EP Impurity P (CAS 1011758-03-4)
Recommended Standards
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- 1-(2-Chlorobenzyl)-3-(4-nitrobenzyl)imidazolidine-2,4,5-trione (CAS 341967-17-7)
- Pitavastatin Impurity 10(R,R) (CAS CATO-C4X-103710)
- Stresscopin-Related Peptide (human) (CAS 348626-74-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com