Quetiapine EP Impurity B-d8 CAS 1189866-35-0
| CAS No. | 1189866-35-0 |
| Molecular Formula | - |
| Molecular Weight | 303.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Quetiapine EP Impurity B-d8 is closely related to deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Quetiapine EP Impurity B-d8 (CAS 1189866-35-0) is a certified pharmaceutical impurity reference standard with the molecular formula C17H9D8N3S and a molecular weight of 303.45 g/mol.
Structurally, Quetiapine EP Impurity B-d8 (C17H9D8N3S) contains deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 303.45 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Quetiapine EP Impurity B-d8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H9D8N3S |
| Molecular Weight | 303.45 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Quetiapine Standards
- Quetiapine impurity 75 (CAS CATO-C4X-124475)
- Quetiapine DBTP N-Methyl Impurity (CAS 1977-09-9)
- Quetiapine EP Impurity T (CAS 5747-46-6)
- Quetiapine Fumarate EP Impurity B (CAS 5747-48-8)
- Quetiapine impurity 82 (CAS CATO-C4X-124482)
- Quetiapine impurity 76 (CAS CATO-C4X-124476)
- Quetiapine EP Impurity P (CAS 1011758-03-4)
- Quetiapine Impurity 68 (CAS CATO-C4X-124468)
Recommended Standards
- 4-Methyl-2-(methylsulfanyl)-7-[3-(methylsulfanyl)phenyl]-5H,6H,7H-pyrrolo[2,3-d]pyrimidine (CAS 338416-20-9)
- Ethinylestradiol-d7 (CAS 2714413-57-5)
- (E,E)-6-α-Ionylidene-4-methylpyran-2-one-d5 (CAS 1331668-72-4)
- Methandienone-d3 (CAS 869287-60-5)
- Cyclophosphamide EP Impurity C HCl (CAS 821-48-7)
- Zolmitriptan Impurity 27 (CAS CATO-C4X-135127)
- Paclitaxel Impurity 18 (CAS CATO-C4X-184218)
- 1-(2-Bromo-6-methoxypyridin-4-yl)ethan-1-one (CAS 1393572-74-1)
- 6-Chloro-N,N-bis(4-methoxybenzyl)-5-(trifluoromethyl)pyrazin-2-amine (CAS 2638502-33-5)
- Sodium Bromite (~80%) (CAS 7486-26-2)
- 5-Bromomethyl-2-fluorobenzeneboronic acid pinacol ester, 97% (CAS 1256360-47-0)
- N,3-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 2246720-26-1)
- 2-(5,6,7,8-Tetrahydro-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)propan-2-ol (CAS 1159554-01-4)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com