Neostigmine impurity 38 CAS CATO-C4X-204238
| CAS No. | CATO-C4X-204238 |
| Molecular Formula | C9H10N2O3 |
| Molecular Weight | 194.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Neostigmine impurity 38 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Neostigmine impurity 38 (CAS CATO-C4X-204238, C9H10N2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Neostigmine impurity 38 (C9H10N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C9H10N2O3 |
| Molecular Weight | 194.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Neostigmine Standards
- Neostigmine Impurity 25 (CAS 76418-45-6)
- Neostigmine impurity 34 (CAS CATO-C4X-204234)
- Neostigmine impurity 36 (CAS CATO-C4X-204236)
- Neostigmine impurity 01 (CAS 618-09-7)
- Neostigmine impurity 35 (CAS CATO-C4X-204235)
- Neostigmine Impurity 26 (CAS 4849-46-1)
- Neostigmine impurity 37 (CAS CATO-C4X-204237)
- Neostigmine Impurity 4 (CAS 19962-04-0)
Recommended Standards
- Dopamine Impurity 105 (CAS CATO-C4X-1908105)
- Sivelestat Impurity 15 (CAS 526-21-6)
- 【禁售品】Aminophylline EP Impurity A(Pentoxifylline EP Impurity F) (CAS 58-08-2)
- Ataluren Impurity 9 (CAS CATO-C4X-30069)
- Dopamine Impurity 114 (CAS CATO-C4X-1908114)
- Amlodipine Besylate EP Impurity F (CAS 140171-66-0)
- Citalopram EP Impurity A HCl (CAS CATO-C4X-110994)
- Relebactam Impurity 81 (CAS CATO-C4X-214481)
- Bosutinib Impurity 16 (CAS CATO-C4X-184716)
- 3-(Methoxycarbonyl)-1,2,2-trimethylcyclopentane-1-carboxylic acid (CAS 306935-15-9)
- (1H-Pyrrolo[3,2-b]pyridin-2-yl)methanamine (CAS 1245808-67-6)
- 7-Iodoisoquinoline (CAS 75476-83-4)
- (s)-2-Amino-2-(4-bromo-2-methoxyphenyl)ethan-1-ol (CAS 1212799-95-5)
- D-[Thr]7-Liraglutide (CAS CATO-C4X-199237)
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