Imatinib Impurity 57 CAS 581076-64-4
| CAS No. | 581076-64-4 |
| Molecular Formula | C8H12N4 |
| Molecular Weight | 164.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Imatinib Impurity 57 (CAS 581076-64-4) is a certified pharmaceutical impurity reference standard with the molecular formula C8H12N4 and a molecular weight of 164.21 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, Imatinib Impurity 57 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 164.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Imatinib Impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12N4 |
| Molecular Weight | 164.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 4 |
Related Imatinib Standards
- Imatinib Mesilate EP Impurity A (CAS 123367-26-0)
- Imatinib EP Impurity A (CAS 55314-16-4)
- Imatinib Impurity 29 (CAS 21900-30-1)
- Imatinib Impurity 63 (CAS 99-94-5)
- Imatinib Impurity 59 (CAS 796738-72-2)
- Imatinib Impurity 45 (CAS 152460-07-6)
- Imatinib Impurity 93 (CAS 870459-88-4)
- Imatinib Impurity 61 (CAS 62-50-0)
Recommended Standards
- 5-(3-amino-1H-pyrazol-4-yl)pentanenitrile (CAS 1011470-70-4)
- Buspirone EP Impurity A (CAS 20980-22-7)
- 3-(piperazin-1-yl)pyridazine 3-Piperazin-1-yl-pyridazine 51047-56-4 A24750 (CAS 51047-56-4)
- 2,2＇-Azobis(2-methylpropionitrile) (CAS 78-67-1)
- Clopidogrel Impurity 114 (CAS CATO-C4X-1029114)
- Nizatidine Impurity 12 (CAS 534-07-6)
- Perampanel Impurity 7 (CAS CATO-C4X-24307)
- Ethyl 1-(4-(5-chlorothiophen-2-yl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 956781-14-9)
- 2-Methoxy-5-methylnicotinonitrile (CAS 149379-73-7)
- 5-(2,3-Bis(tert-butoxycarbonyl)-guanidino)pentanoic acid (CAS 212567-95-8)
- n-(3,4-Dimethoxybenzyl)-1-(pyridin-4-yl)methanamine (CAS 57342-20-8)
- 5-Amino-4-methyl-1-phenyl-1H-pyrazol-3-ol (CAS 934397-98-5)
- 1-Methyl-3-(methylcarbamoyl)-1H-pyrazole-5-carboxylic acid (CAS 1353631-67-0)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com