Azelastine CAS 58581-89-8
| CAS No. | 58581-89-8 |
| Molecular Formula | C22H24ClN3O |
| Molecular Weight | 381.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C22H24ClN3O, Azelastine contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 381.90 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Azelastine (CAS 58581-89-8), molecular formula C22H24ClN3O and molecular weight 381.90 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Azelastine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H24ClN3O |
| Molecular Weight | 381.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Azelastine Standards
- (R)-Azelastine (CAS 143228-84-6)
- (S)-Azelastine (CAS 143228-85-7)
- Azelastine Impurity 51 (CAS CATO-C4X-139651)
- Azelastine-13C,d3 (CAS 1217019-80-1)
- Azelastine-d3 (CAS 758637-88-6)
- Azelastine Impurity 72 (CAS CATO-C4X-139672)
- Azelastine Impurity 20 (CAS 47491-38-3)
- Azelastine impurity 66 (CAS CATO-C4X-139666)
Recommended Standards
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- tert-Butyl(4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)dimethylsilane (CAS 2377611-08-8)
- 3-(1-hydroxycyclopentyl)prop-2-ynoic acid (CAS 54827-89-3)
- Methyl 4-(4-amino-1h-pyrazol-1-yl)butanoate (CAS 1153275-80-9)
- 2-Ethyl-1-methylquinolin-4(1H)-one (CAS 139710-76-2)
- Azetidin-3-yl(pyridin-2-yl)methanone dihydrochloride (CAS 2095410-16-3)
- [3-(3-Chlorobenzyl)-2-oxoimidazolidin-1-yl]acetic acid (CAS 897769-14-1)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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