Tadalafil Impurity 71 CAS 58607-72-0(free base)

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.58607-72-0(free base)
Molecular FormulaC22H22N4O3
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Tadalafil Impurity 71 CAS 58607-72-0(free base) chemical structure

Description

Compared with other compounds in its class, the molecular weight of 426.90 g/mol gives Tadalafil Impurity 71 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Tadalafil Impurity 71 (CAS 58607-72-0(free base)), a pharmacopoeial impurity reference standard (molecular formula C22H22N4O3HCl, MW 426.90 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C22H22N4O3HCl, Tadalafil Impurity 71 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 426.90 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Tadalafil Impurity 71 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC22H22N4O3 HCl
Molecular Weight426.90 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing
Nitrogen Atoms4

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