7-Chloro-2-(3-methoxyphenyl)-8-methylquinoline-4-carboxylic acid CAS 590353-82-5
| CAS No. | 590353-82-5 |
| Molecular Formula | C18H14ClNO3 |
| Molecular Weight | 327.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Chloro-2-(3-methoxyphenyl)-8-methylquinoline-4-carboxylic acid.
7-Chloro-2-(3-methoxyphenyl)-8-methylquinoline-4-carboxylic acid (CAS 590353-82-5), molecular formula C18H14ClNO3 and molecular weight 327.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 7-Chloro-2-(3-methoxyphenyl)-8-methylquinoline-4-carboxylic acid (C18H14ClNO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7-Chloro-2-(3-methoxyphenyl)-8-methylquinoline-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14ClNO3 |
| Molecular Weight | 327.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 7-Chloro-2-(2-methoxyphenyl)-8-methylquinoline-4-carboxylic acid (CAS 862663-10-3)
- 7-Chloro-2-(4-methoxyphenyl)-8-methylquinoline-4-carboxylic acid (CAS 862663-07-8)
- 7-Acetamido Clonazepam (CAS 41993-30-0)
- 7-Chloro-6-methoxy-2-(4-methoxyphenyl)quinoline-4-carbaldehyde (CAS 61576-13-4)
- 4-Butyl-7,8-dihydroxy-2h-chromen-2-one (CAS 19040-68-7)
- 2-Chloro-4-((trifluoromethyl)sulfonyl)pyridine (CAS 2090223-43-9)
- 1’-Oxo Perazine (CAS 91508-47-3)
- 3,3-Difluoro-1-(oxetan-3-yl)pyrrolidine (CAS 1823321-42-1)
- 4-Bromo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine (CAS 1393585-39-1)
- (4-(2,2,2-Trifluoroethoxy)phenyl)hydrazine (CAS 175691-02-8)
- (2-Ethoxyphenyl)(3-hydroxypyrrolidin-1-yl)methanone (CAS 1272305-52-8)
- 4-(Boc-amino)-2-methylthiazole (CAS 848472-61-7)
- 1H-indazol-7-ylmethanamine (CAS 944904-20-5)
- Protein Kinase C (19-36) Peptide (CAS 113731-96-7)
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