7-Chloro-2-(4-methoxyphenyl)-8-methylquinoline-4-carboxylic acid CAS 862663-07-8

Purity 97%+In StockPharmaceutical Standards
CAS No.862663-07-8
Molecular FormulaC18H14ClNO3
Molecular Weight327.76 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-Chloro-2-(4-methoxyphenyl)-8-methylquinoline-4-carboxylic acid CAS 862663-07-8 chemical structure

Description

7-Chloro-2-(4-methoxyphenyl)-8-methylquinoline-4-carboxylic acid (CAS 862663-07-8) is a high-purity analytical reference standard with the molecular formula C18H14ClNO3 and a molecular weight of 327.76 g/mol.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 7-Chloro-2-(4-methoxyphenyl)-8-methylquinoline-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 327.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 7-Chloro-2-(4-methoxyphenyl)-8-methylquinoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H14ClNO3
Molecular Weight327.76 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentCl-containing
Nitrogen Atoms1

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