Flucytosine EP Impurity A CAS 51-21-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.51-21-8
Molecular FormulaC4H3FN2O2
Molecular Weight130.08 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Flucytosine EP Impurity A CAS 51-21-8 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO supplies Flucytosine EP Impurity A (CAS 51-21-8), a pharmacopoeial impurity reference standard (molecular formula C4H3FN2O2, MW 130.08 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C4H3FN2O2, Flucytosine EP Impurity A contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 130.08 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

As a certified reference material (CRM), Flucytosine EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC4H3FN2O2
Molecular Weight130.08 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1957
Halogen ContentF-containing
Nitrogen Atoms2

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