2-Chloro-4-fluoro-N-((4-(6-methylbenzo[d]oxazol-2-yl)phenyl)carbamothioyl)benzamide CAS 593238-85-8
| CAS No. | 593238-85-8 |
| Molecular Formula | C22H15ClFN3O2S |
| Molecular Weight | 439.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Chloro-4-fluoro-N-((4-(6-methylbenzo[d]oxazol-2-yl)phenyl)carbamothioyl)benzamide (C22H15ClFN3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-Chloro-4-fluoro-N-((4-(6-methylbenzo[d]oxazol-2-yl)phenyl)carbamothioyl)benzamide (CAS 593238-85-8), a certified reference material (molecular formula C22H15ClFN3O2S, MW 439.89 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H15ClFN3O2S |
| Molecular Weight | 439.89 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-4-fluoro-N-((3-(5-methylbenzo[d]oxazol-2-yl)phenyl)carbamothioyl)benzamide (CAS 593238-51-8)
- 2-Chloro-4-fluoro-N-((3-(6-methylbenzo[d]oxazol-2-yl)phenyl)carbamothioyl)benzamide (CAS 593238-50-7)
- 4-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-(methylthio)quinazoline (CAS 866138-05-8)
- 5-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-4-yl}-4-phenyl-4H-1,2,4-triazole-3-thiol (CAS 338397-26-5)
- 6-Chloro-3,4-dihydro-N-methyl-3-[[(2,2,2-trifluoroethyl)thio]methyl]-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide (CAS 745-75-5)
- N-(5-chloro-2-methylphenyl)-2-((3-cyano-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinolin-2-yl)thio)acetamide (CAS 626227-77-8)
- 4-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-N-((dimethylamino)methylene)benzamide (CAS 1164512-96-2)
- 2-Chloro-N-{5,6-dimethyl-1-[(3-methylphenyl)methyl]-1H-1,3-benzodiazol-4-yl}benzene-1-sulfonamide (CAS 338423-62-4)
Recommended Standards
- Tadalafil Impurity 183 (CAS CATO-C4X-1087183)
- Losartan-d3 Carboxylic Acid (CAS 1189729-40-5)
- tert-Butyl (2-(3-(3-chlorophenyl)-10-oxopyrazolo[4,3-d]pyrido[1,2-a]pyrimidin-1(10H)-yl)ethyl)carbamate (CAS 1956321-40-6)
- 3-Amino-6-(2-chlorophenyl)-4-(3,4-dimethoxyphenyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 690642-63-8)
- 3-Methyl-2-oxo-1,2-dihydropyridine-4-carbaldehyde (CAS 1227575-61-2)
- Calcium thioglycolate trihydrate crystallized, ≥98.0% (RT) (CAS 65208-41-5)
- N,N-dimethyl-4-(5-((4-nitrobenzylidene)amino)benzo[d]oxazol-2-yl)aniline (CAS 129463-02-1)
- 3-((4-Fluorophenoxy)methyl)pyrrolidine hydrochloride (CAS 1185303-90-5)
- 2-Mercapto-4-(4-methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 200340-05-2)
- 3-(3-Phenyl-1H-1,2,4-triazol-5-yl)piperidinehydrochloride (CAS 1263094-24-1)
- 2,4-Dibromo-6-(trifluoromethoxy)benzene-1-sulfonyl chloride (CAS 1208075-27-7)
- Crizotinib impurity 37 (CAS CATO-C4X-102537)
- Benzyl carbamate (CAS 621-84-1)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com