1’-Acetoxy Midazolam (1.0mg/ml in Acetonitrile) CAS 59468-89-2
| CAS No. | 59468-89-2 |
| Molecular Formula | C20H15ClFN3O2 |
| Molecular Weight | 383.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1’-Acetoxy Midazolam (1.0mg/ml in Acetonitrile) (CAS 59468-89-2), a certified reference material (molecular formula C20H15ClFN3O2, MW 383.80 g/mol) for analytical method development and quality control.
Based on its molecular formula C20H15ClFN3O2, 1’-Acetoxy Midazolam (1.0mg/ml in Acetonitrile) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 383.80 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H15ClFN3O2 |
| Molecular Weight | 383.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Acetoxy Standards
- 4-Acetoxy Midazolam (1.0mg/ml in Acetonitrile) (CAS 59468-84-7)
- 1-Acetoxy-5-bromo-1,2-benziodoxol-3(1H)-one (CAS 1580548-81-7)
- Methyl 2-(2-acetoxy-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-2-(2-chlorophenyl)acetate (CAS 178688-44-3)
- 10-Acetoxy-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl 3-methylbutanoate (CAS 21311-66-0)
- 11-Acetoxy-Δ8-tetrahydrocannabinol (CAS 36871-18-8)
- 6-Acetoxy Belamcandol B (CAS 1388841-30-2)
- (3-Acetoxy-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate (CAS 6161-23-5)
- 3β-Acetoxy-17,17-(ethylenedioxy)androst-5-ene (CAS 17921-59-4)
Recommended Standards
- 1-{3-[4-(4-chlorophenyl)piperazin-1-yl]-5-(trifluoromethyl)pyridin-2-yl}ethan-1-one (CAS 900015-68-1)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2,4,5-trifluorophenyl)acetamide (CAS 303091-66-9)
- 1-(4-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)phenyl)ethan-1-one (CAS 338979-19-4)
- 2-Chloro-4-formyl-6-methoxyphenyl 4-acetamidobenzenesulfonate (CAS 432002-40-9)
- (4E)-3-(Chloromethyl)-4-(2,4,5-trimethoxy-benzylidene)isoxazol-5(4H)-one (CAS 1142199-46-9)
- 2-Cyclopropoxy-3-ethyl-N-methylbenzamide (CAS 1243469-00-2)
- 4-(Difluoromethyl)-5-fluoro-6-hydroxypyridine-3-sulfonamide (CAS 1805507-52-1)
- 4,6-Difluoronicotinic Acid (CAS 849937-91-3)
- 4-(3-(2-Ethoxy-2-oxoethyl)-5-oxo-2,5-dihydro-1h-pyrazol-1-yl)benzoic acid (CAS 852851-71-9)
- Azetidin-3-yl azepane-1-carboxylate (CAS 1526017-69-5)
- 1-(3-Bromo-2-chlorophenyl)ethan-1-one (CAS 161957-62-6)
- Caspofungin Impurity 13 (CAS CATO-C4X-157513)
- 6-Chloro-4-nitronicotinaldehyde (CAS 1060809-78-0)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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