Cimetidine EP Impurity D DiHCl CAS 59660-24-1
| CAS No. | 59660-24-1 |
| Molecular Formula | C9H17N5S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Cimetidine EP Impurity D DiHCl (C9H17N5SHCl) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Cimetidine EP Impurity D DiHCl (CAS 59660-24-1) is a certified pharmaceutical impurity reference standard with the molecular formula C9H17N5SHCl and a molecular weight of 263.79 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Cimetidine EP Impurity D DiHCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H17N5S 2*HCl |
| Molecular Weight | 263.79 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Cimetidine Standards
- Cimetidine Impurity 3 (CAS 10191-60-3)
- Cimetidine carboxamide dihydrochloride (CAS 110592-19-3)
- Cimetidine Impurity 16 (CAS 1185237-29-9)
- Cimetidine EP Impurity B (CAS 138035-55-9)
- Cimetidine Impurity 4 (CAS 1609-06-9)
- Cimetidine Impurity 21 (CAS 182685-55-8)
- Cimetidine impurity 26 (CAS 208447-53-4)
- Cimetidine Impurity 7 (CAS 24771-25-3)
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- 3-Methoxy-2,3-diphenylbutan-2-ol (CAS 93727-39-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com