Piperacillin EP Impurity E CAS 59702-31-7
| CAS No. | 59702-31-7 |
| Molecular Formula | C6H10N2O2 |
| Molecular Weight | 142.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Piperacillin EP Impurity E (CAS 59702-31-7) is a certified pharmaceutical impurity reference standard with the molecular formula C6H10N2O2 and a molecular weight of 142.16 g/mol.
The molecular framework of Piperacillin EP Impurity E (C6H10N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H10N2O2 |
| Molecular Weight | 142.16 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 2 |
Related Piperacillin Standards
- Piperacillin Impurity 75 (CAS CATO-C4X-173275)
- DL-Piperacillin EP Impurity I (CAS 158411-82-6)
- Piperacillin EP Impurity I (CAS 13833-89-1)
- Piperacillin Impurity 26 (CAS 15537-71-0)
- Piperacillin Impurity 53 (CAS 65322-79-4)
- Piperacillin EP Impurity A Hydrochloride (CAS 40688-84-4)
- Piperacillin EP Impurity A Potassium salt (CAS 23277-71-6)
- Piperacillin Monohydrate (CAS 66258-76-2)
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