Riboflavin Impurity N16 CAS 5978-87-0
| CAS No. | 5978-87-0 |
| Molecular Formula | C17H20N4O6 |
| Molecular Weight | 376.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Riboflavin Impurity N16 (CAS 5978-87-0, C17H20N4O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Riboflavin Impurity N16 (C17H20N4O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Riboflavin Impurity N16 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H20N4O6 |
| Molecular Weight | 376.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 4 |
Related Riboflavin Standards
- Riboflavin Vitamin B2 (CAS 5984-80-5)
- Riboflavin Impurity 17 (CAS CATO-C4X-181917)
- Riboflavin Phosphate Hydrate EP Impurity D (CAS CATO-C4X-181927)
- Riboflavin Impurity 33 (CAS 1195174-65-2)
- Riboflavin Impurity 19 (CAS CATO-C4X-181919)
- Riboflavin lmpurity 20 (CAS 57609-95-7)
- Riboflavin Sodium Phosphate Impurity 6 (CAS 36995-95-6)
- Riboflavin Impurity 18 (CAS CATO-C4X-181918)
Recommended Standards
- N-(furan-2-ylmethyl)-2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carbonyl)benzamide (CAS 439107-34-3)
- Tadalafil Impurity N6 (CAS 479545-76-1)
- N-(4-fluoro-3-nitrophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 882749-29-3)
- 20004-62-0 7N3A092A5X Resistomycin 2H-Benzo(cd)pyrene-2,6(1H)-dione, 3,5,7,10-tetrahydroxy-1,1,9-trimethyl- A 3733A 4-08-00-03704 (Beilstein Handbook Reference) Antibiotic A 3733A BRN 2187224 Croceomycin Geliomycin Itamycin UNII-7N3A092A5X (CAS 20004-62-0)
- Ensifentrine impurity 6 (CAS 298680-38-3)
- Dexpanthenol Impurity 28 (CAS CATO-C4X-161328)
- Chlorphenamine impurity 52 (CAS CATO-C4X-118852)
- Ethyl 4-((benzyloxy)methyl)-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazole-5-carboxylate (CAS 1245649-48-2)
- methyl 1-{[4-(2,2,2-trifluoroethoxy)phenyl]methyl}-1H-1,2,4-triazole-3-carboxylate (CAS 1376269-34-9)
- 3-(((4-Chlorophenyl)sulfonyl)methyl)piperidine hydrochloride (CAS 1289387-37-6)
- 6-Amino-5-bromo-3-methyl-1-propyl-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 734546-69-1)
- 6-Bromo-8-cyclopentyl-5-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 362656-25-5)
- 2-[(1-Phenyl-1H-1,2,4-triazol-3-yl)oxy]acetonitrile (CAS 477852-87-2)
- Semaglutide238 (CAS CATO-C4X-2226238)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com