Chlorphenamine impurity 52 CAS CATO-C4X-118852
| CAS No. | CATO-C4X-118852 |
| Molecular Formula | C13H10ClNO2 |
| Molecular Weight | 247.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Chlorphenamine impurity 52 (CAS CATO-C4X-118852), a pharmacopoeial impurity reference standard (molecular formula C13H10ClNO2, MW 247.68 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C13H10ClNO2, Chlorphenamine impurity 52 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 247.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Chlorphenamine impurity 52 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10ClNO2 |
| Molecular Weight | 247.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorphenamine Standards
- Chlorphenamine Impurity 19 (CAS 73486-85-8)
- Chlorphenamine Impurity 26 (CAS CATO-C4X-118826)
- Chlorphenamine Impurity 43 (CAS CATO-C4X-118843)
- Chlorphenamine Impurity 63 (CAS CATO-C4X-118863)
- Chlorphenamine Impurity 69 (CAS CATO-C4X-118869)
- Chlorphenamine Impurity 59 (CAS CATO-C4X-118859)
- Chlorphenamine Impurity 31 (CAS 872811-44-4)
- Chlorphenamine EP Impurity C (CAS 20619-12-9)
Recommended Standards
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- Brimonidine Impurity 15 (CAS 91147-46-5)
- Upadacitinib Impurity 195 (CAS CATO-C4X-2405195)
- Lenalidomide Impurity 8 (CAS 2197414-55-2)
- Desmopressin Impurity 45 (CAS 2251748-64-6)
- 2-Bromo-5-[(carbamoylmethyl)sulfamoyl]benzoic acid (CAS 848290-15-3)
- Methyl 5-chloro-1-methyl-3-phenyl-1H-pyrazole-4-carboxylate (CAS 956764-06-0)
- 2-(Difluoromethoxy)nicotinaldehyde (CAS 2222104-51-8)
- 3-Chloro-5-fluorobenzoic Acid (CAS 25026-64-6)
- Cisatracurium Besilate EP Impurity G Besylate (CAS 96946-46-2)
- 2,2-Diphenylcyclopropanecarboxylic Acid (CAS 7150-12-1)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
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