Riboflavin Impurity 33 CAS 1195174-65-2
| CAS No. | 1195174-65-2 |
| Molecular Formula | C17H20N4O6 |
| Molecular Weight | 376.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Riboflavin Impurity 33 (CAS 1195174-65-2), a pharmacopoeial impurity reference standard (molecular formula C17H20N4O6, MW 376.36 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Riboflavin Impurity 33 (C17H20N4O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Riboflavin Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H20N4O6 |
| Molecular Weight | 376.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 4 |
Related Riboflavin Standards
- Riboflavin Impurity N16 (CAS 5978-87-0)
- Riboflavin Vitamin B2 (CAS 5984-80-5)
- Riboflavin Impurity 17 (CAS CATO-C4X-181917)
- Riboflavin Phosphate Hydrate EP Impurity D (CAS CATO-C4X-181927)
- Riboflavin Impurity 19 (CAS CATO-C4X-181919)
- Riboflavin lmpurity 20 (CAS 57609-95-7)
- Riboflavin Sodium Phosphate Impurity 6 (CAS 36995-95-6)
- Riboflavin Impurity 18 (CAS CATO-C4X-181918)
Recommended Standards
- Carbidopa Impurity 18 (CAS CATO-C4X-231018)
- Vitamin B2 (CAS 83-88-5)
- Loganic Acid (CAS 22255-40-9)
- Cilnidipine Impurity 9 (CAS 74936-76-8)
- Cetirizine Impurity 8 (CAS 1384888-64-5)
- Polmacoxib Impurity 4 Sodium Salt (CAS 1778703-67-5)
- Azilsartan Impurity 118 (CAS CATO-C4X-1096118)
- 6-((Tert-butoxycarbonyl)amino)bicyclo[3.1.0]Hexane-3-carboxylic acid (CAS 2168763-80-0)
- 4-(4-Methoxyphenyl)-2,3-dihydro-1H-benzo[b][1,4]diazepine (CAS 283610-65-1)
- 1-(2-Fluorophenyl)-2-(3-fluorophenyl)ethanone (CAS 1183418-91-8)
- N-(4-Methoxybenzyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 393820-11-6)
- 7-Bromobenzo[b]thiophene-2-carboxylic acid (CAS 19075-59-3)
- 2-(6-Isopropoxynaphthalen-1-yl)propane-1,3-diol (CAS 1015856-05-9)
- Neuropeptide Y (13-36) (porcine) (CAS 113662-54-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com