Iopamidol Impurity 52 CAS 60166-91-8
| CAS No. | 60166-91-8 |
| Molecular Formula | C13H8Cl2I3NO5 |
| Molecular Weight | 709.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Iopamidol Impurity 52 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Iopamidol Impurity 52 (CAS 60166-91-8), a pharmacopoeial impurity reference standard (molecular formula C13H8Cl2I3NO5, MW 709.83 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Iopamidol Impurity 52 (C13H8Cl2I3NO5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H8Cl2I3NO5 |
| Molecular Weight | 709.83 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Iopamidol Standards
- Iopamidol Impurity 44 (CAS CATO-C4X-145044)
- Iopamidol Impurity 45 (CAS CATO-C4X-145045)
- Iopamidol EP Impurity A (CAS 60166-98-5)
- Iopamidol EP Impurity D (CAS 87932-11-4)
- Iopamidol Impurity 33 (CAS CATO-C4X-145033)
- Iopamidol Impurity 49 (CAS CATO-C4X-145049)
- Iopamidol Impurity 46 (CAS CATO-C4X-145046)
- Iopamidol Impurity 43 (CAS CATO-C4X-145043)
Recommended Standards
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- Faropenem Impurity 2 (CAS CATO-C4X-12892)
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- 1-(2,5-Dichlorobenzyl)piperidine-3-carboxylic acid (CAS 896045-33-3)
- 4-Phenyldinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin (CAS 158154-47-3)
- 2,6-Bis(benzyloxy)-3-(4-bromophenyl)pyridine (CAS 2736510-43-1)
- 4,5-Dibromo-3-methylthiophene-2-carbaldehyde (CAS 30153-49-2)
- 1,3-Bis(2-bromophenyl)urea (CAS 175278-34-9)
- FMRF-Like Neuropeptide (CAS 121801-61-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com