Iopamidol EP Impurity A CAS 60166-98-5
| CAS No. | 60166-98-5 |
| Molecular Formula | C14H18I3N3O6 |
| Molecular Weight | 705.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 705.02 g/mol gives Iopamidol EP Impurity A distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Iopamidol EP Impurity A (CAS 60166-98-5), a pharmacopoeial impurity reference standard (molecular formula C14H18I3N3O6, MW 705.02 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Iopamidol EP Impurity A (C14H18I3N3O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 705.02 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Iopamidol EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H18I3N3O6 |
| Molecular Weight | 705.02 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 3 |
Related Iopamidol Standards
- Iopamidol EP Impurity D (CAS 87932-11-4)
- Iopamidol Impurity 44 (CAS CATO-C4X-145044)
- Iopamidol Impurity 45 (CAS CATO-C4X-145045)
- Iopamidol Impurity 52 (CAS 60166-91-8)
- Iopamidol Impurity 33 (CAS CATO-C4X-145033)
- Iopamidol Impurity 49 (CAS CATO-C4X-145049)
- Iopamidol Impurity 43 (CAS CATO-C4X-145043)
- Iopamidol Impurity 46 (CAS CATO-C4X-145046)
Recommended Standards
- 2-((2,6-Dimethylquinolin-4-yl)thio)ethyl acetate (CAS 63908-20-3)
- Iohexol Impurity 31 (CAS 1096689-22-3)
- Eosin5-isothiocyanate (CAS 60520-47-0)
- Iohexol EP Impurity J (CAS 76801-93-9)
- Gliquidone Impurity 9 (CAS 58202-95-2)
- Ribociclib Impurity 32 (CAS CATO-C4X-310032)
- Resmetirom impurity 68 (CAS CATO-C4X-291268)
- 4'-Nitro-1H,1'H,1''H-4,3':5',4''-terpyrazole (CAS 164668-48-8)
- Di-t-butoxydiacetoxysilane (CAS 13170-23-5)
- Etoposide impurity 20 (CAS CATO-C4X-202420)
- Ethyl 2-(cyclopropylamino)-2-(4-hydroxyphenyl)acetate (CAS 1218114-66-9)
- 1-(1-Phenyl-2-(trimethylsilyl)ethyl)-1H-benzo[d][1,2,3]triazole (CAS 219700-98-8)
- 4-Bromo-2,3-dihydroxybenzoic acid (CAS 61203-52-9)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com