Valproate Impurity 47 CAS 6065-63-0

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.6065-63-0
Molecular FormulaC13H24O4
Molecular Weight244.33 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Valproate Impurity 47 CAS 6065-63-0 chemical structure

Description

Valproate Impurity 47 (CAS 6065-63-0) is a certified pharmaceutical impurity reference standard with the molecular formula C13H24O4 and a molecular weight of 244.33 g/mol.

The molecular framework of Valproate Impurity 47 (C13H24O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H24O4
Molecular Weight244.33 g/mol
Purity>95%
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1958

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