Minocycline 9-Methylamino Impurity CAS 607402-73-3
| CAS No. | 607402-73-3 |
| Molecular Formula | C24H30N4O7 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 522.98 g/mol gives Minocycline 9-Methylamino Impurity distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Minocycline 9-Methylamino Impurity (CAS 607402-73-3) is a certified pharmaceutical impurity reference standard with the molecular formula C24H30N4O7HCl and a molecular weight of 522.98 g/mol.
Minocycline 9-Methylamino Impurity (C24H30N4O7HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H30N4O7 HCl |
| Molecular Weight | 522.98 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Minocycline Standards
- Minocycline Impurity N1 (CAS 10118-89-5)
- Minocycline (CAS 10118-90-8)
- Minocycline EP Impurity F (CAS 1075240-33-3)
- Minocycline Hydrochloride Dihydrate (CAS 128420-71-3)
- Minocycline EP Impurity H (CAS 1346598-44-4)
- Minocycline Hydrochloride (CAS 13614-98-7)
- Minocycline Impurity 26 (CAS 149934-16-7)
- Minocycline impurity 73 (CAS 156263-28-4)
Recommended Standards
- Ensifentrine Impurity 2 (CAS 75535-95-4)
- Dantrolene Related Compound B (CAS 57268-33-4)
- Baloxavir Marboxil Impurity 224 (CAS CATO-C4X-2108224)
- 5-Methyl-1-(2-nitrophenyl)-1h-pyrazole (CAS 1247439-67-3)
- 3-Methylbenzofuran-4,7-dione (CAS 20958-13-8)
- (2R,5R)-2-Cyclopropyl-5-phenylmorpholine (CAS 1349829-31-7)
- O-(4-Amino-5-fluoropyrimidin-2-yl)-tert-butyl N-methyl-N-hydroxycarbamate (CAS 1174376-60-3)
- (6S)-6-Ethynyl-5-azaspiro[2.4]heptane (CAS 2410398-36-4)
- UDP-D-Glucose (sodium salt) (CAS 7333-33-7)
- Semaglutide impurity 66 (CAS CATO-C4X-222666)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com