Flumethasone Impurity 1 CAS 60895-22-9
| CAS No. | 60895-22-9 |
| Molecular Formula | C22H28F2O5 |
| Molecular Weight | 410.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Flumethasone Impurity 1 (C22H28F2O5) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 410.45 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Flumethasone Impurity 1 (CAS 60895-22-9), a pharmacopoeial impurity reference standard (molecular formula C22H28F2O5, MW 410.45 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Flumethasone Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H28F2O5 |
| Molecular Weight | 410.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F-containing |
Related Flumethasone Standards
- Flumethasone Methyl (CAS CATO-C4X-19106)
- Flumethasone (CAS 2135-17-3)
- Flumethasone-d3 (CAS CATO-CCAD303315)
- Flumethasone Impurity 7 (CAS 28400-50-2)
- Flumethasone Impurity 3 (CAS CATO-C4X-19103)
- Flumethasone Impurity 4 (CAS CATO-C4X-19104)
- Flumethasone Impurity 5 (CAS CATO-C4X-19105)
- Flumethasone Acetate (CAS 2823-42-9)
Recommended Standards
- Fluticasone Impurity 67 (CAS CATO-C4X-165067)
- Flumetasone Impurity 15 (CAS CATO-C4X-191015)
- Fluticasone Impurity 61 (CAS CATO-C4X-165061)
- Fluticasone Impurity 58 (CAS CATO-C4X-165058)
- Pazufloxacin Impurity 23 (CAS CATO-C4X-233223)
- Trandolapril Impurity 8 (CAS CATO-C4X-17708)
- Ceftaroline Fosamil Impurity C54 (CAS 1240196-56-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com