Trandolapril Impurity 8 CAS CATO-C4X-17708
| CAS No. | CATO-C4X-17708 |
| Molecular Formula | C16H21NO2 |
| Molecular Weight | 259.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Trandolapril Impurity 8 (CAS CATO-C4X-17708), a pharmacopoeial impurity reference standard (molecular formula C16H21NO2, MW 259.34 g/mol) used for the identification and quantification of trace impurities in APIs.
Trandolapril Impurity 8 (C16H21NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Trandolapril Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H21NO2 |
| Molecular Weight | 259.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Trandolapril Standards
- Trandolapril Impurity 3 (2S,3aR,7aS) (CAS 144540-71-6)
- Trandolapril Impurity 10 (CAS 83508-14-9)
- Trandolapril Impurity 11 (CAS 87679-38-7)
- Trandolapril Impurity 15 (CAS 760916-37-8)
- Trandolapril Impurity 7 (CAS CATO-C4X-17707)
- Trandolapril Impurity 14 (CAS CATO-C4X-177014)
- Trandolapril EP Impurity E (Trandolaprilate) (CAS 87679-71-8)
- Trandolapril EP Impurity D (CAS 149881-40-3)
Recommended Standards
- Ibandronic Impurity 19 (CAS CATO-C4X-224419)
- Ramelteon (CAS 196597-26-9)
- (R)-Ramelteon (CAS 196597-27-0)
- Sulfathiazole-D4 (CAS 1020719-89-4)
- Dronedarone Impurity 73 (CAS 5337-04-2)
- Montelukast Impurity 36 (CAS 142569-69-5)
- Tenofovir alafenamide Impurity 90 (CAS CATO-C4X-179790)
- 2,3-Dihydroimidazo[2,1-b]benzothiazol-6-amine (CAS 78291-99-3)
- tert-Butyl 4-(4-chloro-5-methylpyrimidin-2-yl)-2-methylpiperazine-1-carboxylate (CAS 1261232-46-5)
- 6-Chloro-3-quinolinamine (CAS 1051372-60-1)
- 4-Chloro-6-methoxy-3-(1H)indazole carboxaldehyde (CAS 885520-41-2)
- Acuminatin (CAS 143601-07-4)
- 4-(5-((4-Fluorophenoxy)methyl)-1,2,4-oxadiazol-3-yl)benzaldehyde (CAS 1119450-77-9)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com