Bromhexine Hydrochloride CAS 611-75-6
| CAS No. | 611-75-6 |
| Molecular Formula | C14H20Br2N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bromhexine Hydrochloride.
Bromhexine Hydrochloride (CAS 611-75-6) is a high-purity analytical reference standard with the molecular formula C14H20Br2N2HCl and a molecular weight of 412.59 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution, Bromhexine Hydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 412.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Bromhexine Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H20Br2N2 HCl |
| Molecular Weight | 412.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromhexine Standards
- Bromhexine Impurity 35 (CAS 100-60-7)
- Bromhexine impurity 59 (CAS 100669-81-6)
- Bromhexine Impurity 51 (CAS 100669-82-7)
- Bromhexine EP Impurity D(2HCl) (CAS 10076-98-9)
- Bromhexine Impurity 22 (CAS 114059-99-3)
- Bromhexine Impurity 17 (CAS 114390-40-8)
- Bromhexine Impurity N3 (CAS 114390-41-9)
- Bromhexine impurity 60 (CAS 1261676-18-9)
Recommended Standards
- n-(3-Methylbutyl)piperidine-4-carboxamide hydrochloride (CAS 1172804-95-3)
- Ethyl 5,6-diamino-2-(dimethylamino)pyrimidine-4-carboxylate (CAS 90769-45-2)
- 2-Amino-N-(quinolin-3-yl)acetamide (CAS 1155901-78-2)
- 2-(4-Bromo-2-fluorophenyl)-4-methylpyridine (CAS 1187168-33-7)
- 4-[(4-Fluorophenyl)sulfonyl]-2-methyl-1,3,4-benzoxadiazepin-5(4H)-one (CAS 865658-76-0)
- Dioctyldineodecanoatetin (CAS 68299-15-0)
- 2-(5-Methoxy-1h-indol-3-yl)acetamide (CAS 2452-25-7)
- Baricitinib Impurity 116 (CAS CATO-C4X-2260116)
- (2E,4E)-2-Cyano-5-phenylpenta-2,4-dienamide (CAS 138175-50-5)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
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