Prednisolone Impurity 19 CAS 61549-70-0
| CAS No. | 61549-70-0 |
| Molecular Formula | C21H26O6 |
| Molecular Weight | 374.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Prednisolone Impurity 19 is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Prednisolone Impurity 19 (CAS 61549-70-0) is a certified pharmaceutical impurity reference standard with the molecular formula C21H26O6 and a molecular weight of 374.43 g/mol.
Prednisolone Impurity 19 (C21H26O6) contains a flavonoid core, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H26O6 |
| Molecular Weight | 374.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
Related Prednisolone Standards
- Prednisolone impurity 59 (CAS CATO-C4X-173759)
- Prednisolone EP Impurity D (CAS 16355-29-6)
- Prednisolone EP Impurity E (CAS 95815-58-0)
- 6α-Methyl Prednisolone-d3 (CAS CATO-C4X-173725)
- Prednisolone-d8 (Major) (CAS CATO-C4X-191924)
- Prednisolone-d8 (CAS CATO-CCAD302219)
- Prednisolone-d8 (CAS CATO-LCAD302219-ME)
- Prednisolone-D6 (CAS CATO-C4X-191930)
Recommended Standards
- Prednisone Impurity 5 (CAS 215095-77-5)
- Ketoprofen Impurity 68 (CAS CATO-C4X-147168)
- Bevantolol Impurity 16 (CAS CATO-C4X-241116)
- Conjugated Estrogens EP Impurity A (CAS 56050-04-5)
- Anastrozole Impurity 35 (CAS 2384659-42-9)
- Venetoclax Impurity 33 (CAS CATO-C4X-249533)
- Citalopram EP Impurity F HCl (CAS 1644389-68-3)
- (S)-5-Aminopiperidin-2-one hydrochloride (CAS 672883-95-3)
- (4-Bromo-6-chloro-1H-indazol-3-yl)methanamine (CAS 1936212-22-4)
- Methyl 2-acetyl-3-methyl-4-oxopentanoate (CAS 84912-11-8)
- N,N-DiBoc-4-methylaniline (CAS 1623005-34-4)
- Ethyl 4-(1-ethyl-3,5-dimethyl-1H-pyrazol-4-yl)-2,4-dioxobutanoate (CAS 956935-27-6)
- Risperidone Impurity 19 (CAS 84162-82-3)
- Semaglutide Impurity 12 (CAS CATO-C4X-222612)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com