Prednisolone EP Impurity E CAS 95815-58-0
| CAS No. | 95815-58-0 |
| Molecular Formula | C21H28O6 |
| Molecular Weight | 376.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C21H28O6, Prednisolone EP Impurity E contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 376.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Prednisolone EP Impurity E (CAS 95815-58-0), a pharmacopoeial impurity reference standard (molecular formula C21H28O6, MW 376.44 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Prednisolone EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H28O6 |
| Molecular Weight | 376.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
Related Prednisolone Standards
- Prednisolone EP Impurity D (CAS 16355-29-6)
- 6α-Methyl Prednisolone-d3 (CAS CATO-C4X-173725)
- Prednisolone Impurity 19 (CAS 61549-70-0)
- Prednisolone impurity 59 (CAS CATO-C4X-173759)
- Prednisolone-d8 (Major) (CAS CATO-C4X-191924)
- Prednisolone-d8 (CAS CATO-CCAD302219)
- Prednisolone-d8 (CAS CATO-LCAD302219-ME)
- Prednisolone Acetate EP Impurity E (CAS 4380-55-6)
Recommended Standards
- Mycophenolic Acid Impurity 9 (CAS CATO-C4X-21229)
- Budesonide Impurity 80 (CAS CATO-C4X-138980)
- Bisphenol A-bis(2,3-dihydroxypropyl) Ether (Mixture of Diastereomers) (CAS 5581-32-8)
- Budesonide impurity 59 (CAS 34647-56-8)
- Pemetrexed Impurity 16 (CAS CATO-C4X-172616)
- Cephalexin EP Impurity C (CAS 72528-40-6)
- Glycerol Impurity 18 Disodium Salt (CAS CATO-C4X-217118)
- 2-(Pyridin-3-ylmethyl)quinuclidin-3-amine (CAS 1391013-37-8)
- N-[4-(sec-Butoxy)benzyl]-3-(tetrahydro-2-furanylmethoxy)aniline (CAS 1040681-93-3)
- 1,2,3,4-tetrahydro-1,5-dimethylnaphthalene 1,5-DMT 1,5-dimethyl-1,2,3,4-tetrahydronaphthalene 1,5-dimethyltetralin 21564-91-0 CHEBI:48650 (CAS 21564-91-0)
- 5-Amino-1,3-dihydro-2λ6-benzothiophene-2,2-dione (CAS 70654-85-2)
- 2-methylimidazo[1,2-a]pyrimidine-3-carboxylic acid (CAS 90830-11-8)
- tert-Butyl 2-chloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate (CAS 1211581-47-3)
- Insulin Glargine (CAS 160337-95-1)
Why CATO?
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