4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one CAS 618073-02-2
| CAS No. | 618073-02-2 |
| Molecular Formula | C24H26FN3O5 |
| Molecular Weight | 455.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one.
4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one (CAS 618073-02-2) is a high-purity analytical reference standard with the molecular formula C24H26FN3O5 and a molecular weight of 455.48 g/mol.
4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one (C24H26FN3O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H26FN3O5 |
| Molecular Weight | 455.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoro Standards
- 2-(5-Fluoro-3-(4-((4-fluorophenyl)sulfonyl)benzyl)-2-methyl-1H-indol-1-yl)acetic acid (CAS 1161864-21-6)
- 2-(4-Fluoro-phenyl)-4,4-dimethoxy-1-[4-(4-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-butan-1-one (CAS 1227268-99-6)
- 2-(3-(2-((3-Fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile (CAS 1239875-86-5)
- 5-Fluoro-1-(4-fluorobenzyl)pyrimidine-2,4(1H,3H)-dione (CAS 86547-17-3)
- GDC-0623 (5-((2-Fluoro-4-Iodophenyl)amino)-N-(2-Hydroxyethoxy)imidazo[1,5-a]pyridine-6-Carboxamide) (CAS 1168091-68-6)
- N-(4-Fluoro-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-2-iodobenzamide (CAS 865248-73-3)
- 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-phenyl-1H-pyrrol-2(5H)-one (CAS 609796-29-4)
- (11β)-9-Fluoro-11,17-dihydroxy-21-[(methylsulfonyl)oxy]pregna-1,4-diene-3,20-dione (CAS 382-66-1)
Recommended Standards
- 1-(2-(Diethylamino)ethyl)-4-(3-fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 618074-09-2)
- Methyl 4-[4-(naphthalene-2-sulfonyl)piperazin-1-yl]-3-nitrobenzoate (CAS 478246-58-1)
- 4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}-1-(3,4,5-trimethoxybenzoyl)piperidine (CAS 1775302-55-0)
- Isavuconazole Impurity 41 (CAS CATO-C4X-123641)
- 1-(Pyridin-3-ylmethyl)cyclopropan-1-amine (CAS 1251260-28-2)
- (R)-Norfenfluramine Hydrochloride (CAS 41538-52-7)
- 1-Bromo-3-chloro-5-ethoxybenzene (CAS 1881329-54-9)
- 3-(3-Nitrophenyl)isoxazole-5-carboxylic acid (CAS 1022083-09-5)
- N-(2,6-dichloro-4-sulfamoylphenyl)propanamide (CAS 1094361-88-2)
- Coclaurine Impurity 113 (CAS 2158198-78-6(TFA Salt))
- 2-(2-Carboxyphenyl)quinoline-4-carboxylic acid (CAS 60539-01-7)
- 2-(1,3-Dioxooctahydro-2H-4,7-methanoisoindol-2-yl)acetic acid (CAS 26785-97-7)
- AST-1306 (CAS 897383-62-9)
- Semaglutide impurity 249 (CAS CATO-C4X-2226249)
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