4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-phenyl-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one CAS 618073-94-2
| CAS No. | 618073-94-2 |
| Molecular Formula | C24H19FN2O3 |
| Molecular Weight | 402.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-phenyl-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618073-94-2), a certified reference material (molecular formula C24H19FN2O3, MW 402.42 g/mol) for analytical method development and quality control.
The molecular framework of 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-phenyl-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (C24H19FN2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-phenyl-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H19FN2O3 |
| Molecular Weight | 402.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
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- 2-(S-(fluoro(phenyl)methyl)-N-tosylsulfinimidoyl)phenolate (CAS 1260143-68-7)
- 7-Fluoro-4-(4-fluorophenyl)-2-[4-(trifluoromethyl)phenyl]-1,2-dihydrophthalazin-1-one (CAS 339009-72-2)
- 5-Fluoro-3-(methoxymethoxy)-8-((triisopropylsilyl)ethynyl)naphthalen-1-ol (CAS 2771460-07-0)
- 7-Fluoro-3-(methoxymethoxy)-8-((triisopropylsilyl)ethynyl)naphthalen-1-ol (CAS 2621932-35-0)
- 5-Fluoro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227268-55-4)
- 6-Fluoro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227270-19-0)
- 4-Fluoro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227270-45-2)
Recommended Standards
- 4-(1-Methylethoxy)dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin (CAS 720667-00-5)
- N-((5-((2-((2-Ethoxyphenyl)amino)-2-oxoethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)furan-2-carboxamide (CAS 851862-52-7)
- 1-cyclopentyl-4-methyl-1H-pyrazolo[3,4-b]pyridin-6-yl 3-nitrobenzenesulfonate (CAS 929972-81-6)
- Setipiprant (CAS 866460-33-5)
- N-[2-(3-Piperidinyl)ethyl]-N-propyl-1-propanaminedihydrochloride (CAS 1220035-65-3)
- 4-(2-METHOXYPHENYLSULFANYL)PIPERIDINE HCL (CAS 1170287-04-3)
- 4-(4-Heptylphenyl)-2-methyl-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile (CAS 439108-64-2)
- Cefditoren Impurity 36 (CAS CATO-C4X-135836)
- Ceritinib Impurity 45 (CAS CATO-C4X-104845)
- 1-Fluoroundecane (CAS 506-05-8)
- 2-(4-Amino-2-chlorophenyl)-2-phenylacetonitrile (CAS 4760-53-6)
- 3-(3-Chloro-4-methylphenyl)-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one (CAS 1082366-91-3)
- Methyl 1-(aminomethyl)cyclohexane-1-carboxylate (CAS 99092-04-3)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com