4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-propoxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one CAS 618073-92-0
| CAS No. | 618073-92-0 |
| Molecular Formula | C27H25FN2O4 |
| Molecular Weight | 460.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-propoxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618073-92-0), molecular formula C27H25FN2O4 and molecular weight 460.50 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-propoxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (C27H25FN2O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 460.50 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-propoxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H25FN2O4 |
| Molecular Weight | 460.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-5-(4-isopropylphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618074-59-2)
- Methyl 4-(3-(3-fluoro-4-methylbenzoyl)-4-hydroxy-5-oxo-1-(pyridin-3-ylmethyl)-2,5-dihydro-1H-pyrrol-2-yl)benzoate (CAS 618075-99-3)
- 2-((2-Fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 869357-68-6)
- 4-Fluoro-4-methyl-2-(2,2,2-trifluoro-1-(4'-(methylsulfonyl)biphenyl-4-yl)ethylamino)pentanoic acid (CAS 1415559-56-6)
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- 2-((3-Fluoro-4-methoxyphenyl)amino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxamide (CAS 1092829-93-0)
- trans-4-[4-[4-(5-Fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydro-1(2H)-pyridinyl]cyclohexaneacetic acid (CAS 1628301-84-7)
- 4-Fluoro-N-{2-[({5-oxo-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-3-yl}methyl)sulfanyl]phenyl}benzamide (CAS 477868-79-4)
Recommended Standards
- 4-Bromo-3-chlorophenyl (2E)-3-(6-bromo-2H-1,3-benzodioxol-5-yl)prop-2-enoate (CAS 478259-31-3)
- 2-(9,9-Dihexyl-9H-fluoren-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 264925-45-3)
- Diethyl {[1-(triphenylmethyl)-1H-imidazol-4-yl]methyl}phosphonate (CAS 473659-21-1)
- 4’-Desmethyl-6’-tosylmycophenolic Acid (CAS 171808-03-0)
- 4-(3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)morpholine (CAS 2377608-89-2)
- H-Lys(Z)-OtBu · HCl (CAS 5978-22-3)
- (2E)-1-(4-Methoxyphenyl)-3-(3-methylphenyl)prop-2-en-1-one (CAS 1287761-30-1)
- 5,5-Dimethyl-2-(naphthalen-2-yloxy)oxazol-4(5H)-one (CAS 73372-82-4)
- Methyl 4-(benzo[c][1,2,5]thiadiazol-5-ylmethoxy)benzoate (CAS 874834-02-3)
- (5-Bromo-2-(trifluoromethyl)pyridin-4-yl)methanol (CAS 1359828-97-9)
- 1,2-Diphenyl-1H-indole-3-carbaldehyde (CAS 29329-99-5)
- Methyl (3-chloro-5-(trifluoromethyl)-pyridin-2-yloxy)acetate (CAS 1053658-71-1)
- 3-(1-(Difluoromethyl)-1h-pyrazol-3-yl)-6,7,8,9-tetrahydro-5h-[1,2,4]triazolo[4,3-a]azepine (CAS 1174884-34-4)
- Cyclolinopeptide B (CAS 193139-41-2)
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