Ponatinib Impurity 33 CAS CATO-C4X-226933
| CAS No. | CATO-C4X-226933 |
| Molecular Formula | C24H17F3N4O |
| Molecular Weight | 434.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ponatinib Impurity 33 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Ponatinib Impurity 33 (CAS CATO-C4X-226933, C24H17F3N4O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ponatinib Impurity 33 (C24H17F3N4O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 434.41 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C24H17F3N4O |
| Molecular Weight | 434.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Ponatinib Standards
- Ponatinib Impurity 13 (CAS CATO-C4X-226913)
- Ponatinib Impurity 53 (CAS CATO-C4X-226953)
- Ponatinib Impurity 60 (CAS CATO-C4X-226960)
- Ponatinib Impurity N72 (CAS 957147-18-1)
- Ponatinib Impurity 20 (CAS CATO-C4X-226920)
- Ponatinib Impurity 42 (CAS CATO-C4X-226942)
- Ponatinib Impurity 31 (CAS CATO-C4X-226931)
- Ponatinib Impurity 9 (CAS CATO-C4X-22699)
Recommended Standards
- Fluvoxamine EP Impurity C (CAS 259526-43-7)
- 1,3-Dimethyl 5,5-dicyano-4-(4-fluorophenyl)-2-hydroxy-6-phenylcyclohex-1-ene-1,3-dicarboxylate (CAS 1212220-50-2)
- 9-(4-Bromophenyl)-3,6-di-tert-butyl-9H-carbazole (CAS 601454-33-5)
- 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-5-(3-hydroxyphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618074-57-0)
- Bosentan Impurity 14 (CAS 1355251-10-3)
- Ruxolitinib Impurity 101 (CAS CATO-C4X-2058101)
- Etomidate Impurity 7 (CAS 66514-85-0)
- 4-Nitro-1H-imidazole-1-carbonitrile (CAS 716316-19-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com