Glyceryl Trinitrate Solution EP Impurity C CAS 620-12-2
| CAS No. | 620-12-2 |
| Molecular Formula | C3H7NO5 |
| Molecular Weight | 137.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Glyceryl Trinitrate Solution EP Impurity C is closely related to an amino-acid-derived structure, an amide group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Glyceryl Trinitrate Solution EP Impurity C (CAS 620-12-2, C3H7NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Glyceryl Trinitrate Solution EP Impurity C (C3H7NO5) contains an amino-acid-derived structure, an amide group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C3H7NO5 |
| Molecular Weight | 137.09 g/mol |
| Purity | 1.0 mg/mL in Acetonitrile |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Glyceryl Standards
- Glyceryl Trinitrate Solution EP Impurity B (CAS 624-43-1)
- Glyceryl Trinitrate Impurity 6 (CAS 1433993-67-9)
- Glyceryl Trinitrate Solution EP Impurity D (CAS 621-65-8)
- Glyceryl Trinitrate Solution EP Impurity E (CAS 623-87-0)
- α-Glyceryl Anthranilate (CAS 71574-35-1)
- Glyceryl Valproate Impurity 1 (CAS 77656-37-2)
- Glyceryl Trinitrate Impurity 8 (CAS CATO-C4X-22318)
- Glyceryl Monocaprate (CAS 2277-23-8)
Recommended Standards
- (Prop-2-yn-1-yl)(2,2,2-trifluoroethyl)amine (CAS 1020931-14-9)
- 5-Ethynylisoxazole-3-carboxylic acid (CAS 89488-59-5)
- 5-Cyano-1H-imidazole-2-carboxylic acid (CAS 1026882-55-2)
- 5-Cyano-2-furancarboxylic Acid (CAS 212197-74-5)
- Fudosteine Impurity 15 HCl (CAS CATO-C4X-144715)
- Etamsylate Impurity 1 (CAS CATO-C4X-28541)
- Lacosamide EP Impurity F (R-isomer) (CAS 175481-38-6)
- (E)-{[5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methylidene}amino 4-chlorobenzoate (CAS 318284-51-4)
- 2-(4-((Benzyl(methyl)amino)methyl)piperidin-1-yl)ethanol (CAS 1353985-27-9)
- 2-(Isopropylthio)-3-((2,4,6-trichlorophenyl)diazenyl)-1H-indole (CAS 478042-26-1)
- 2-Chloro-N-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)acetamide (CAS 496056-68-9)
- tert-Butyl (3-mercaptophenyl)carbamate (CAS 195622-56-1)
- (4-Chlorophenyl)(3,5-dimethylphenyl)methanol (CAS 844683-41-6)
- Hexapeptide-9 (CAS 1228371-11-6)
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