Fenfluramine Impurity 8 CAS 621-45-4
| CAS No. | 621-45-4 |
| Molecular Formula | C10H11F3O |
| Molecular Weight | 204.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fenfluramine Impurity 8.
As a process- or degradation-related impurity, Fenfluramine Impurity 8 (CAS 621-45-4, C10H11F3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Fenfluramine Impurity 8 (C10H11F3O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Fenfluramine Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11F3O |
| Molecular Weight | 204.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Fenfluramine Standards
- Nor-Fenfluramine (CAS 1886-26-6)
- Fenfluramine Impurity 2 (CAS 21235-67-6)
- Fenfluramine Impurity 3 (CAS 713-45-1)
- Fenfluramine Impurity 4 (CAS 21906-39-8)
- DL-Fenfluramine (CAS 458-24-2)
- Fenfluramine Impurity 1 (CAS 52777-74-9)
- Fenfluramine Impurity 1 (CAS 19023-40-6)
- Fenfluramine hydrochloride (CAS 16105-77-4)
Recommended Standards
- Ethyl 2-(4,5-dicyano-1H-imidazol-1-yl)acetate (CAS 939901-65-2)
- Methyl 2-(1-Tetrazolyl)benzoate (CAS 309279-56-9)
- Benzeneacetic acid, 4-(1H-tetrazol-1-yl)- (CAS 462068-57-1)
- Methyl 3-(1-Tetrazolyl)benzoate (CAS 309279-57-0)
- Arbidol Impurity 3 (CAS 153633-10-4)
- Elagolix Impurity 99 (CAS CATO-C4X-206899)
- Nicardipine Impurity 43 (CAS CATO-C4X-171043)
- 1-(2-Cyclopropyl-6-ethylpyrimidin-4-yl)piperidin-4-amine (CAS 1707399-85-6)
- 1-(6-(Ethoxycarbonyl)-5,6,7,8-tetrahydropyrido[4,3-c]pyridazin-3-yl)-1H-imidazole-4-carboxylic acid (CAS 1713463-23-0)
- 7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine dihydrochloride (CAS 2492326-14-2)
- Ethyl 7-fluoro-4-methoxy-1H-indole-2-carboxylate (CAS 1197943-55-7)
- 1-Bromo-5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)pentan-2-one (CAS 101931-62-8)
- 5-Iodo-2-(2,2,2-trifluoroacetamido)benzoic acid (CAS 445479-81-2)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com