5-Amino-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazole-4-carbonitrile CAS 94038-76-3
| CAS No. | 94038-76-3 |
| Molecular Formula | C10H5ClF3N5 |
| Molecular Weight | 287.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Amino-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazole-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 5-Amino-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazole-4-carbonitrile (CAS 94038-76-3), a certified reference material (molecular formula C10H5ClF3N5, MW 287.63 g/mol) for analytical method development and quality control.
Structurally, 5-Amino-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazole-4-carbonitrile (C10H5ClF3N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 287.63 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H5ClF3N5 |
| Molecular Weight | 287.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Amino Standards
- 4-Amino-2-(difluoromethyl)-5-nitropyridine-3-sulfonyl chloride (CAS 1805014-71-4)
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- 4-Amino-6-(difluoromethyl)-5-nitropyridine-2-sulfonyl chloride (CAS 1806004-09-0)
- 5-Amino-4-chloro-2-(3-(difluoromethoxy)phenyl)pyridazin-3(2H)-one (CAS 62270-15-9)
- 3-Amino-5-chloro-2'-(trifluoromethoxy)biphenyl (CAS 1261554-01-1)
- (5-Amino-1-(3-chlorophenyl)-1H-pyrazol-4-yl)(furan-2-yl)methanone (CAS 618091-66-0)
- 1-(2-Amino-3-chloro-6-fluorophenyl)naphthalen-2-ol (CAS 1424386-52-6)
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Recommended Standards
- 2-Chloro-4-(difluoromethyl)-5-nitropyridine-3-sulfonamide (CAS 1807090-73-8)
- 2-Chloro-6-(pentafluoroethylthio)benzonitrile (CAS 1159512-56-7)
- 6-Chloro-5-(difluoromethyl)-4-nitropyridine-2-sulfonamide (CAS 1807090-60-3)
- 4-Acetyl-6-(trifluoromethyl)pyridine-2-sulfonyl chloride (CAS 1393547-31-3)
- 4-Bromo-1-methyl-5-nitro-1H-pyrazole-3-carboxylic acid (CAS 84547-91-1)
- Regorafenib Impurity 40 (CAS 2711-18-4)
- 1,6-Dibromo-cyclohexene (CAS 17202-32-3)
- 113873-67-9 L-Glutamic acid, L-alpha-aspartyl-L-leucyl-L-alpha-aspartyl-L-valyl-L-prolyl-L-isoleucyl-L-prolylglycyl-L-arginyl-L-phenylalanyl-L-alpha-aspartyl-L-arginyl-L-arginyl-L-valyl-L-seryl-L-valyl-L-alanyl-L-alanyl- (CAS 113873-67-9)
- Ethyl 2-(tert-butyl)-6-formylpyrimidine-4-carboxylate (CAS 944900-83-8)
- 8-Chloro-6-fluoroquinazolin-4(3H)-one (CAS 1564541-96-3)
- 5-((1S,3S,4S)-4-((tert-butyldimethylsilyl)oxy)-3-fluorocyclohexyl)pyrazin-2-amine (CAS 1715032-85-1)
- (E)-3-(3-Bromophenyl)acrylic acid (CAS 14473-91-7)
- 5,7-Dimethyl-5,7-dihydrofuro[3,4-b]pyrazine (CAS 35162-56-2)
- Semaglutide Impurity 157 (x TFA Salt) (CAS CATO-C4X-2226157)
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